Common grounds for erectile dysfunction and coronary artery disease
PURPOSE OF REVIEWEvidence is accumulating to consider erectile dysfunction as a vascular problem. This review focuses on background, pathophysiological mechanisms and clinical evidence of the link between erectile dysfunction and coronary artery disease. RECENT FINDINGSThe link between erectile dysf...
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| Veröffentlicht in: | Current opinion in urology 2004-11, Vol.14 (6), p.361-365 |
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| container_title | Current opinion in urology |
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| creator | Montorsi, Piero Ravagnani, Paolo M Galli, Stefano Rotatori, Francesco Briganti, Alberto Salonia, Andrea Dehò, Federico Montorsi, Francesco |
| description | PURPOSE OF REVIEWEvidence is accumulating to consider erectile dysfunction as a vascular problem. This review focuses on background, pathophysiological mechanisms and clinical evidence of the link between erectile dysfunction and coronary artery disease.
RECENT FINDINGSThe link between erectile dysfunction and coronary artery disease is suggested by the following. (1) Common risk factors for atherosclerosis are frequently found in erectile dysfunction. (2) Erectile dysfunction is frequently found in vascular syndromes such as coronary artery disease, hypertension, cerebrovascular disease, peripheral arterial disease and diabetes. (3) A similar pathogenic involvement of the NO pathway leading to impairment of endothelium-dependent vasodilatation and late structural vascular abnormalities is shared by erectile dysfunction and vascular disorders. Given this background, the ‘artery-size hypothesis’ is a recently proposed pathophysiological mechanism to explain the link between sexual dysfunction and myocardial ischemia.
SUMMARYErectile dysfunction and coronary artery disease appear to be linked tightly each other. |
| doi_str_mv | 10.1097/00042307-200411000-00012 |
| format | Article |
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RECENT FINDINGSThe link between erectile dysfunction and coronary artery disease is suggested by the following. (1) Common risk factors for atherosclerosis are frequently found in erectile dysfunction. (2) Erectile dysfunction is frequently found in vascular syndromes such as coronary artery disease, hypertension, cerebrovascular disease, peripheral arterial disease and diabetes. (3) A similar pathogenic involvement of the NO pathway leading to impairment of endothelium-dependent vasodilatation and late structural vascular abnormalities is shared by erectile dysfunction and vascular disorders. Given this background, the ‘artery-size hypothesis’ is a recently proposed pathophysiological mechanism to explain the link between sexual dysfunction and myocardial ischemia.
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RECENT FINDINGSThe link between erectile dysfunction and coronary artery disease is suggested by the following. (1) Common risk factors for atherosclerosis are frequently found in erectile dysfunction. (2) Erectile dysfunction is frequently found in vascular syndromes such as coronary artery disease, hypertension, cerebrovascular disease, peripheral arterial disease and diabetes. (3) A similar pathogenic involvement of the NO pathway leading to impairment of endothelium-dependent vasodilatation and late structural vascular abnormalities is shared by erectile dysfunction and vascular disorders. Given this background, the ‘artery-size hypothesis’ is a recently proposed pathophysiological mechanism to explain the link between sexual dysfunction and myocardial ischemia.
SUMMARYErectile dysfunction and coronary artery disease appear to be linked tightly each other.</description><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Humans</subject><subject>Impotence, Vasculogenic - complications</subject><subject>Impotence, Vasculogenic - epidemiology</subject><subject>Male</subject><issn>0963-0643</issn><issn>1473-6586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kTtPwzAQgC0EoqXwF1AmtoAdO04yooiXVIkFZsuxzzSQxMVOVPXfc6UFJgbrztZ3D30mJGH0mtGquKGUiozTIs0wYQyvKR6WHZE5EwVPZV7KYzKnleQplYLPyFmM7zuiYvyUzFguM1mWdE7q2ve9H5K34KfBxsT5kEAAM7YdJHYb3TRgjoAebGJ88IMO20SHETDYNoKOcE5OnO4iXBzigrze373Uj-ny-eGpvl2mhuO8NNPS0kyUTeOoKYRgmZOAK0HO8VEYaqtGGplrqW1paF65pqKWSRC84c6WfEGu9n3XwX9OEEfVt9FA1-kB_BSVLNBJLisEyz1ogo8xgFPr0Pa4uGJU7QSqH4HqV6D6Foill4cZU9OD_Ss8GENA7IGN71BC_OimDQS1At2NK_Xfx_AvtC164g</recordid><startdate>200411</startdate><enddate>200411</enddate><creator>Montorsi, Piero</creator><creator>Ravagnani, Paolo M</creator><creator>Galli, Stefano</creator><creator>Rotatori, Francesco</creator><creator>Briganti, Alberto</creator><creator>Salonia, Andrea</creator><creator>Dehò, Federico</creator><creator>Montorsi, Francesco</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200411</creationdate><title>Common grounds for erectile dysfunction and coronary artery disease</title><author>Montorsi, Piero ; Ravagnani, Paolo M ; Galli, Stefano ; Rotatori, Francesco ; Briganti, Alberto ; Salonia, Andrea ; Dehò, Federico ; Montorsi, Francesco</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3562-2a6d0248bbf0c74412f6e012e5348b4c0d9b6c65a6ad8c059fb90d16e43b3fd83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - epidemiology</topic><topic>Humans</topic><topic>Impotence, Vasculogenic - complications</topic><topic>Impotence, Vasculogenic - epidemiology</topic><topic>Male</topic><toplevel>online_resources</toplevel><creatorcontrib>Montorsi, Piero</creatorcontrib><creatorcontrib>Ravagnani, Paolo M</creatorcontrib><creatorcontrib>Galli, Stefano</creatorcontrib><creatorcontrib>Rotatori, Francesco</creatorcontrib><creatorcontrib>Briganti, Alberto</creatorcontrib><creatorcontrib>Salonia, Andrea</creatorcontrib><creatorcontrib>Dehò, Federico</creatorcontrib><creatorcontrib>Montorsi, Francesco</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Montorsi, Piero</au><au>Ravagnani, Paolo M</au><au>Galli, Stefano</au><au>Rotatori, Francesco</au><au>Briganti, Alberto</au><au>Salonia, Andrea</au><au>Dehò, Federico</au><au>Montorsi, Francesco</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Common grounds for erectile dysfunction and coronary artery disease</atitle><jtitle>Current opinion in urology</jtitle><addtitle>Curr Opin Urol</addtitle><date>2004-11</date><risdate>2004</risdate><volume>14</volume><issue>6</issue><spage>361</spage><epage>365</epage><pages>361-365</pages><issn>0963-0643</issn><eissn>1473-6586</eissn><abstract>PURPOSE OF REVIEWEvidence is accumulating to consider erectile dysfunction as a vascular problem. This review focuses on background, pathophysiological mechanisms and clinical evidence of the link between erectile dysfunction and coronary artery disease.
RECENT FINDINGSThe link between erectile dysfunction and coronary artery disease is suggested by the following. (1) Common risk factors for atherosclerosis are frequently found in erectile dysfunction. (2) Erectile dysfunction is frequently found in vascular syndromes such as coronary artery disease, hypertension, cerebrovascular disease, peripheral arterial disease and diabetes. (3) A similar pathogenic involvement of the NO pathway leading to impairment of endothelium-dependent vasodilatation and late structural vascular abnormalities is shared by erectile dysfunction and vascular disorders. Given this background, the ‘artery-size hypothesis’ is a recently proposed pathophysiological mechanism to explain the link between sexual dysfunction and myocardial ischemia.
SUMMARYErectile dysfunction and coronary artery disease appear to be linked tightly each other.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>15626880</pmid><doi>10.1097/00042307-200411000-00012</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0963-0643 |
| ispartof | Current opinion in urology, 2004-11, Vol.14 (6), p.361-365 |
| issn | 0963-0643 1473-6586 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Coronary Artery Disease - complications Coronary Artery Disease - epidemiology Humans Impotence, Vasculogenic - complications Impotence, Vasculogenic - epidemiology Male |
| title | Common grounds for erectile dysfunction and coronary artery disease |
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