Prion genetics: new rules for a new kind of gene

Just as nucleic acids can carry out enzymatic reactions, proteins can be genes. These heritable infectious proteins (prions) follow unique genetic rules that enable their identification: reversible curing, inducible "spontaneous generation," and phenotype surprises. Most prions are based o...

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Veröffentlicht in:	Annual review of genetics 2004-01, Vol.38 (1), p.681-707
Hauptverfasser:	Wickner, Reed B, Edskes, Herman K, Ross, Eric D, Pierce, Michael M, Baxa, Ulrich, Brachmann, Andreas, Shewmaker, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - chemistry Amyloid - genetics Animals Cricetinae Genetics Humans Mice Models, Biological Molecular Chaperones Nucleic acids Phenotype Podospora - genetics Podospora - metabolism Prion Diseases - genetics Prions - genetics Prions - metabolism Protein Binding Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Yeasts - genetics Yeasts - metabolism
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