Double-blind trial of levodopa/carbidopa/entacapone versus levodopa/carbidopa in early Parkinson's disease

We performed a 39‐week, randomized, double‐blind, multicenter study to compare the efficacy, safety, and tolerability of levodopa/carbidopa/entacapone (LCE, Stalevo) with levodopa/carbidopa (LC, Sinemet IR) in patients with early Parkinson's disease (PD). Four hundred twenty‐three patients with...

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Veröffentlicht in:	Movement disorders 2009-03, Vol.24 (4), p.541-550
Hauptverfasser:	Hauser, Robert A., Panisset, Michel, Abbruzzese, Giovanni, Mancione, Linda, Dronamraju, Nalina, Kakarieka, Algirdas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antiparkinson Agents - therapeutic use Biological and medical sciences Carbidopa - therapeutic use Catechols - therapeutic use Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Double-Blind Method Drug Therapy, Combination entacapone Female Humans levodopa Levodopa - therapeutic use Male Medical sciences Middle Aged Neurology Nitriles - therapeutic use Outcome Assessment (Health Care) - methods Parkinson Disease - drug therapy Parkinson's disease Severity of Illness Index Stalevo treatment UPDRS
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