In vitro and in vivo genetic stability studies of a human adenovirus type 5 recombinant rabies glycoprotein vaccine (ONRAB)

Abstract Investigation into the genetic stability of a replication-competent human adenovirus rabies glycoprotein recombinant (ONRAB) developed for use as an oral vaccine for wildlife rabies prevention is of major importance due to the vaccine's intended placement in the environment. Using a co...

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Veröffentlicht in:	Vaccine 2009-05, Vol.27 (20), p.2662-2668
Hauptverfasser:	Knowles, M. Kimberly, Roberts, Danielle, Craig, Sheona, Sheen, Mary, Nadin-Davis, Susan A, Wandeler, Alexander I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus Allergy and Immunology Animals Antibodies, Monoclonal - immunology Applied microbiology Biological and medical sciences Cell Line DNA, Viral - chemistry DNA, Viral - genetics Drug Stability Epitopes - immunology Fundamental and applied biological sciences. Psychology Human adenovirus Mice Microbiology Miscellaneous Oral vaccine Rabies - prevention & control Rabies glycoprotein Rabies Vaccines - genetics Rabies Vaccines - immunology Recombinant virus stability Sequence Analysis, DNA Sigmodon hispidus Sigmodontinae Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Synthetic - genetics Vaccines, Synthetic - immunology Virology
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