Modeling of glucose regulation and insulin-signaling pathways

A model of glucose regulation system was combined with a model of insulin-signaling pathways in this study. A feedback loop was added to link the transportation of glucose into cells (by GLUT4 in the insulin-signaling pathways) and the insulin-dependent glucose uptake in the glucose regulation model...

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Bibliographische Detailangaben

Veröffentlicht in:	Molecular and cellular endocrinology 2009-05, Vol.303 (1), p.13-24
Hauptverfasser:	Chew, Yin Hoon, Shia, Yoke Lin, Lee, Chew Tin, Majid, Fadzilah Adibah Abdul, Chua, Lee Suan, Sarmidi, Mohamad Roji, Aziz, Ramlan Abdul
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological Transport Feedback, Physiological Glucose - metabolism Glucose regulation Glucose Transporter Type 4 - metabolism Glucose uptake GLUT4 translocation Humans Insulin - metabolism Insulin signaling Metabolic modeling Models, Biological Signal Transduction
Online-Zugang:	Volltext
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