EFFECTS OF VITAMIN E AND SESAMIN ON HYPERTENSION AND CEREBRAL THROMBOGENESIS IN STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE RATS

SUMMARY The preventive effects of sesamin, a lignan from sesame oil and vitamin E on hypertension and thrombosis were examined using stroke‐prone spontaneously hypertensive rats (SHRSP). Animals at 5 weeks of age were separated into four groups: (i) control group; (ii) vitamin E group, which was giv...

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Veröffentlicht in:	Clinical and experimental pharmacology & physiology 2004-12, Vol.31 (s2), p.S24-S26
Hauptverfasser:	Noguchi, Takanori, Ikeda, Katsumi, Sasaki, Yasuto, Yamamoto, Junichiro, Yamori, Yukio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antihypertensive Agents - therapeutic use Antioxidants - therapeutic use blood pressure Blood Pressure - drug effects cerebral thrombus Deoxyguanosine - analogs & derivatives Deoxyguanosine - urine Dioxoles - therapeutic use Fibrinolytic Agents - therapeutic use Hypertension - drug therapy Hypertension - physiopathology Hypertension - urine Intracranial Thrombosis - prevention & control Lignans - therapeutic use Rats Rats, Inbred SHR sesamin SHRSP Stroke - prevention & control Vitamin E - therapeutic use vitamin E
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