Obese Women Exhibit Differences in Ovarian Metabolites, Hormones, and Gene Expression Compared with Moderate-Weight Women

Context: Obese women experience longer times to conception, even if they are young and cycling regularly, which is suggestive of alterations in ovarian function during the periconceptual period. Objective: This study sought to determine whether there are alterations in the preovulatory follicular en...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2009-05, Vol.94 (5), p.1533-1540
Hauptverfasser:	Robker, Rebecca L., Akison, Lisa K., Bennett, Brenton D., Thrupp, Penny N., Chura, Lindsay R., Russell, Darryl L., Lane, Michelle, Norman, Robert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Androgens - metabolism Biological and medical sciences Body Mass Index Body Weight - genetics Body Weight - physiology C-Reactive Protein - metabolism Cumulus Cells - metabolism Endocrinopathies Feeding. Feeding behavior Female Follicular Fluid - metabolism Fundamental and applied biological sciences. Psychology Gene Expression - physiology Granulosa Cells - metabolism Hormones - biosynthesis Hormones - genetics Hormones - metabolism Humans Medical sciences Obesity - genetics Obesity - metabolism Oocytes - physiology Ovary - metabolism Reproduction Reverse Transcriptase Polymerase Chain Reaction RNA - biosynthesis RNA - isolation & purification Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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