Atherosclerosis and Vascular Injury: The Effect of a Perivascular Nitric Oxide Donor in a Cholesterol-Fed Rabbit Model

Nitric oxide (NO) has been shown to prevent neointimal hyperplasia and decrease atherosclerosis in several animal models. It is a major modulator of vascular homeostasis and has vasoprotective effects against atherosclerosis. However, NO-based therapies with such purposes have not been used in the c...

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Veröffentlicht in:	Annals of vascular surgery 2009-05, Vol.23 (3), p.392-397
Hauptverfasser:	Abbasi, Kyomars, Anvari, Maryam Sotudeh, Mahdanian, Abolfazl, Ahmadi, Seyed Hosein, Rabbani, Shahram, Karimi, Abbasali, Marzban, Mehrab, Shalileh, Keivan, Ashrafinia, Narges
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - drug effects Aorta - injuries Aorta - pathology Atherosclerosis - etiology Atherosclerosis - pathology Atherosclerosis - prevention & control Catheterization - adverse effects Cholesterol, Dietary Dimethylpolysiloxanes Disease Models, Animal Dosage Forms Drug Carriers Hypercholesterolemia - complications Hypercholesterolemia - drug therapy Hypercholesterolemia - etiology Hypercholesterolemia - pathology Male Nitric Oxide Donors - pharmacology Rabbits Severity of Illness Index Surgery Triazenes - pharmacology
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