FITC-albumin as a marker for assessment of endothelial permeability in mice: comparison with 125I-albumin

Transvascular transport of labeled-albumin is used to study endothelial permeability in experimental murine models of pulmonary infections. But radio-tagged albumin necessitates heavy safety procedures in terms of storage, manipulation and evacuation. The authors tested fluorescein isothiocyanate-ta...

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Veröffentlicht in:	Experimental lung research 2009-05, Vol.35 (4), p.263-271
Hauptverfasser:	Boutoille, D, Marechal, X, Pichenot, Marie, Chemani, C, Guery, B, Faure, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Capillary Permeability Endothelium, Vascular - metabolism Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescein-5-isothiocyanate - pharmacokinetics Iodine Radioisotopes - pharmacokinetics Methods Mice Pseudomonas aeruginosa Reproducibility of Results Respiratory Tract Infections - diagnosis Respiratory Tract Infections - pathology Serum Albumin - pharmacokinetics
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