Single-Molecule Approach to Understanding Multivalent Binding Kinetics

Multivalency results from the simultaneous binding of multiple ligands with multiple receptors. Understanding the effect of multivalency on binding kinetics in molecular and cellular systems may aid the development of new types of therapeutics or countermeasures to pathogen infection. Here, we descr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Annals of the New York Academy of Sciences 2009-04, Vol.1161 (1), p.74-82
Hauptverfasser:	Sulchek, Todd, Friddle, Raymond, Ratto, Timothy, Albrecht, Huguette, DeNardo, Sally, Noy, Aleksandr
Format:	Artikel
Sprache:	eng
Schlagworte:	atomic force microscopy cancer Elasticity force spectroscopy Kinetics Mucin-1 - analysis Mucin-1 - chemistry Spectrum Analysis - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!