Cytomegalovirus Pneumonitis Presenting Small Nodular Opacities
Diffuse pulmonary small nodules and pyrexia suddenly developed in a 27-year-old woman during immunosuppressive treatment for viral-associated hemophagocytic syndrome. Miliary tuberculosis was suspected, however, bone marrow biopsy did not support the diagnosis. Lung biopsy revealed interstitial pneu...
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| Veröffentlicht in: | Internal Medicine 2004, Vol.43(12), pp.1198-1200 |
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| container_title | Internal Medicine |
| container_volume | 43 |
| creator | SHIMADA, Akiko KOGA, Takeharu SHIMADA, Mari KITAJIMA, Takao MITSUI, Takashi SATA, Michio AIZAWA, Hisamichi |
| description | Diffuse pulmonary small nodules and pyrexia suddenly developed in a 27-year-old woman during immunosuppressive treatment for viral-associated hemophagocytic syndrome. Miliary tuberculosis was suspected, however, bone marrow biopsy did not support the diagnosis. Lung biopsy revealed interstitial pneumonitis admixed with characteristic inclusion-bearing cells, and cytomegalovirus (CMV) DNA was demonstrated in polymerase chain reaction using bronchoalveolar lavage cells, establishing the diagnosis of CMV pneumonitis. No other opportunistic pathogens were identified, and the pneumonitis was subsided due to administration of gancyclovir. The present case illustrates CMV pneumonitis as a differential diagnosis for small nodular opacities which develop in immunocompromised patients. |
| doi_str_mv | 10.2169/internalmedicine.43.1198 |
| format | Article |
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Miliary tuberculosis was suspected, however, bone marrow biopsy did not support the diagnosis. Lung biopsy revealed interstitial pneumonitis admixed with characteristic inclusion-bearing cells, and cytomegalovirus (CMV) DNA was demonstrated in polymerase chain reaction using bronchoalveolar lavage cells, establishing the diagnosis of CMV pneumonitis. No other opportunistic pathogens were identified, and the pneumonitis was subsided due to administration of gancyclovir. The present case illustrates CMV pneumonitis as a differential diagnosis for small nodular opacities which develop in immunocompromised patients.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.43.1198</identifier><identifier>PMID: 15645659</identifier><language>eng</language><publisher>Tokyo: The Japanese Society of Internal Medicine</publisher><subject>Adult ; Biological and medical sciences ; Cytomegalovirus Infections - diagnosis ; Cytomegalovirus Infections - diagnostic imaging ; Cytomegalovirus Infections - pathology ; cytomegalovirus pneumonitis ; Diagnosis, Differential ; Female ; General aspects ; Humans ; immunocompromised host ; Lung - diagnostic imaging ; Lung - pathology ; Medical sciences ; miliary ; opportunistic infection ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - diagnostic imaging ; Pneumonia, Viral - pathology ; Radiography</subject><ispartof>Internal Medicine, 2004, Vol.43(12), pp.1198-1200</ispartof><rights>2004 by The Japanese Society of Internal Medicine</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c612t-7fec7b11d7e51349b0a995de4e0e1a0943ee269c758853b446e6196bb95778ae3</citedby><cites>FETCH-LOGICAL-c612t-7fec7b11d7e51349b0a995de4e0e1a0943ee269c758853b446e6196bb95778ae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16525985$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15645659$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SHIMADA, Akiko</creatorcontrib><creatorcontrib>KOGA, Takeharu</creatorcontrib><creatorcontrib>SHIMADA, Mari</creatorcontrib><creatorcontrib>KITAJIMA, Takao</creatorcontrib><creatorcontrib>MITSUI, Takashi</creatorcontrib><creatorcontrib>SATA, Michio</creatorcontrib><creatorcontrib>AIZAWA, Hisamichi</creatorcontrib><title>Cytomegalovirus Pneumonitis Presenting Small Nodular Opacities</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Diffuse pulmonary small nodules and pyrexia suddenly developed in a 27-year-old woman during immunosuppressive treatment for viral-associated hemophagocytic syndrome. Miliary tuberculosis was suspected, however, bone marrow biopsy did not support the diagnosis. Lung biopsy revealed interstitial pneumonitis admixed with characteristic inclusion-bearing cells, and cytomegalovirus (CMV) DNA was demonstrated in polymerase chain reaction using bronchoalveolar lavage cells, establishing the diagnosis of CMV pneumonitis. No other opportunistic pathogens were identified, and the pneumonitis was subsided due to administration of gancyclovir. The present case illustrates CMV pneumonitis as a differential diagnosis for small nodular opacities which develop in immunocompromised patients.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cytomegalovirus Infections - diagnosis</subject><subject>Cytomegalovirus Infections - diagnostic imaging</subject><subject>Cytomegalovirus Infections - pathology</subject><subject>cytomegalovirus pneumonitis</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>immunocompromised host</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Medical sciences</subject><subject>miliary</subject><subject>opportunistic infection</subject><subject>Pneumonia, Viral - diagnosis</subject><subject>Pneumonia, Viral - diagnostic imaging</subject><subject>Pneumonia, Viral - pathology</subject><subject>Radiography</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1rGzEQhkVJqB23f6Hspbmtu5JW0upSCCZfEOpA0rOYlceujFbrSruF_PvIeEkg9DIzMM_MvPMSUtBqyajUP1wYMAbwHW6cdQGXNV9SqptPZE55rUvFuDgj80rTpmQ5zMhFSvuq4o3S7DOZUSFrIYWek5-rl6HvcAe-_-fimIrHgGPXBze4XEdMGAYXdsVTB94Xv_rN6CEW6wPYTGD6Qs634BN-nfKC_L65fl7dlQ_r2_vV1UNpJWVDqbZoVUvpRqE4Cmwr0FpssMYKKVS65ohMaqtE0wje1rVESbVsWy2UagD5glye9h5i_3fENJjOJYveQ8B-TEYqRvO3KoPNCbSxTyni1hyi6yC-GFqZo3fmo3em5uboXR79Nt0Y29x8H5zMysD3CYBkwW8jBOvSOycFEzrrX5D1idunAXb4BkAcnPX4fwVsikcpb6T9A9Fg4K_86JqH</recordid><startdate>20041201</startdate><enddate>20041201</enddate><creator>SHIMADA, Akiko</creator><creator>KOGA, Takeharu</creator><creator>SHIMADA, Mari</creator><creator>KITAJIMA, Takao</creator><creator>MITSUI, Takashi</creator><creator>SATA, Michio</creator><creator>AIZAWA, Hisamichi</creator><general>The Japanese Society of Internal Medicine</general><general>Japanese Society of Internal Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20041201</creationdate><title>Cytomegalovirus Pneumonitis Presenting Small Nodular Opacities</title><author>SHIMADA, Akiko ; KOGA, Takeharu ; SHIMADA, Mari ; KITAJIMA, Takao ; MITSUI, Takashi ; SATA, Michio ; AIZAWA, Hisamichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c612t-7fec7b11d7e51349b0a995de4e0e1a0943ee269c758853b446e6196bb95778ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cytomegalovirus Infections - diagnosis</topic><topic>Cytomegalovirus Infections - diagnostic imaging</topic><topic>Cytomegalovirus Infections - pathology</topic><topic>cytomegalovirus pneumonitis</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>immunocompromised host</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - pathology</topic><topic>Medical sciences</topic><topic>miliary</topic><topic>opportunistic infection</topic><topic>Pneumonia, Viral - diagnosis</topic><topic>Pneumonia, Viral - diagnostic imaging</topic><topic>Pneumonia, Viral - pathology</topic><topic>Radiography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SHIMADA, Akiko</creatorcontrib><creatorcontrib>KOGA, Takeharu</creatorcontrib><creatorcontrib>SHIMADA, Mari</creatorcontrib><creatorcontrib>KITAJIMA, Takao</creatorcontrib><creatorcontrib>MITSUI, Takashi</creatorcontrib><creatorcontrib>SATA, Michio</creatorcontrib><creatorcontrib>AIZAWA, Hisamichi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SHIMADA, Akiko</au><au>KOGA, Takeharu</au><au>SHIMADA, Mari</au><au>KITAJIMA, Takao</au><au>MITSUI, Takashi</au><au>SATA, Michio</au><au>AIZAWA, Hisamichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytomegalovirus Pneumonitis Presenting Small Nodular Opacities</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. 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| subjects | Adult Biological and medical sciences Cytomegalovirus Infections - diagnosis Cytomegalovirus Infections - diagnostic imaging Cytomegalovirus Infections - pathology cytomegalovirus pneumonitis Diagnosis, Differential Female General aspects Humans immunocompromised host Lung - diagnostic imaging Lung - pathology Medical sciences miliary opportunistic infection Pneumonia, Viral - diagnosis Pneumonia, Viral - diagnostic imaging Pneumonia, Viral - pathology Radiography |
| title | Cytomegalovirus Pneumonitis Presenting Small Nodular Opacities |
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