Pilot trial of autologous dendritic cells loaded with tumor lysate(s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma

Immunotherapy with autologous dendritic cells (DCs) loaded with tumor lysate(s) from allogeneic tumor cell lines is a novel strategy to induce immune responses in cancer patients. We report on a pilot trial of autologous DCs pulsed with tumor cell lysate derived from allogeneic medullary thyroid car...

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Veröffentlicht in:	Oncology reports 2009-06, Vol.21 (6), p.1585-1592
Hauptverfasser:	BACHLEITNER-HOFMANN, Thomas, FRIED, Josef, NIEDERLE, Bruno, GNANT, Michael, STIFT, Anton, HASSLER, Michaela, HAYDEN, Hubert, DUBSKY, Peter, SACHET, Monika, RIEDER, Erwin, PFRAGNER, Roswitha, BROSTJAN, Christine, RISS, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biomarkers, Tumor - blood Calcitonin - blood Cancer Vaccines Carcinoma, Medullary - diagnosis Carcinoma, Medullary - immunology Carcinoma, Medullary - secondary Carcinoma, Medullary - therapy Cell Line, Tumor Dendritic Cells - immunology Dendritic Cells - transplantation Disease Progression Endocrinopathies Female Humans Immunotherapy, Adoptive - adverse effects Interferon-gamma - metabolism Male Malignant tumors Medical sciences Middle Aged Pilot Projects T-Lymphocytes, Cytotoxic - immunology Thyroid Neoplasms - diagnosis Thyroid Neoplasms - immunology Thyroid Neoplasms - secondary Thyroid Neoplasms - therapy Thyroid. Thyroid axis (diseases) Time Factors Transplantation, Autologous Treatment Outcome Tumors
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