Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study

Deposits of abnormally phosphorylated tau protein are found in numerous neurodegenerative disorders; the ‘tauopathies’, which include Alzheimer's and Pick's diseases, but tau pathology is also found in the ageing brain. Variation in tau pathology in brain ageing and its relationship to dev...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2009-05, Vol.132 (5), p.1324-1334
Hauptverfasser:	Lace, G., Savva, G. M., Forster, G., de Silva, R., Brayne, C., Matthews, F. E., Barclay, J. J., Dakin, L., Ince, P. G., Wharton, S. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over ageing Aging - metabolism Aging - pathology Aging - psychology Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer Disease - psychology Alzheimer's disease Amyloid beta-Peptides - analysis Amyloid beta-Peptides - metabolism Biological and medical sciences Chi-Square Distribution Cognition Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases dementia Disease Progression Entorhinal Cortex - chemistry Entorhinal Cortex - metabolism Entorhinal Cortex - pathology Female Hippocampus - chemistry Hippocampus - metabolism Hippocampus - pathology Humans Immunohistochemistry Longitudinal Studies Male Medical sciences Neural Pathways - physiology neurodegeneration Neurology tau tau Proteins - analysis tau Proteins - metabolism
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