Insulin-like Growth Factor Binding Protein 5: Contribution to Growth and Differentiation of Neuroblastoma Cells

: Neuroblastoma (NB) is a childhood tumor that depends on insulin‐like growth factors (IGFs) for its growth and metastatic spread. Some metastatic NBs acquire independence from the paracrine support of IGF by activating autocrine production of IGF‐2. Insulin‐like growth factor binding protein‐5 (IGF...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2004-12, Vol.1028 (1), p.59-68
Hauptverfasser:	CESI, VINCENZO, VITALI, ROBERTA, TANNO, BARBARA, GIUFFRIDA, MARIA LAURA, SESTI, FABIOLA, MANCINI, CAMILLO, RASCHELLÀ, GIUSEPPE
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Cell Differentiation Cell Line, Tumor Cell Proliferation differentiation DNA Primers - chemistry Dose-Response Relationship, Drug Humans IGF-2 IGFBP-5 Insulin-Like Growth Factor Binding Protein 5 - genetics Insulin-Like Growth Factor Binding Protein 5 - metabolism Insulin-Like Growth Factor II - metabolism LAN-5 Luciferases - metabolism Mitosis Models, Genetic Mutation neuroblastoma Neuroblastoma - metabolism Phenotype Plasmids - metabolism Promoter Regions, Genetic Recombinant Proteins - chemistry retinoic acid Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Transfection Tretinoin - metabolism Tretinoin - pharmacology
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