Salivary Transcriptome Diagnostics for Oral Cancer Detection

Purpose: Oral fluid (saliva) meets the demand for noninvasive, accessible, and highly efficient diagnostic medium. Recent discovery that a large panel of human RNA can be reliably detected in saliva gives rise to a novel clinical approach, salivary transcriptome diagnostics. The purpose of this stud...

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Veröffentlicht in:	Clinical cancer research 2004-12, Vol.10 (24), p.8442-8450
Hauptverfasser:	Li, Yang, St John, Maie A R, Zhou, Xiaofeng, Kim, Yong, Sinha, Uttam, Jordan, Richard C K, Eisele, David, Abemayor, Elliot, Elashoff, David, Park, No-Hee, Wong, David T
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - genetics Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Case-Control Studies Female Gene Expression Profiling Humans Male Medical sciences Middle Aged Mouth Neoplasms - diagnosis Mouth Neoplasms - genetics Mouth Neoplasms - metabolism Oligonucleotide Array Sequence Analysis Otorhinolaryngology. Stomatology Pharmacology. Drug treatments Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism RNA, Neoplasm - isolation & purification Saliva - chemistry Transcription, Genetic Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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