Comparison of the Cytotoxicity of 4 Preparations of Anti-T-cell Globulins in Various Hematological Malignancies

Objective: The cytotoxic effects of 4 ATG preparations (Thymoglobulin®, ATG-Fresenius®, Lymphoglobulin® and ATGAM®) in hematological malignancies were compared. Materials and Methods: Myeloma, myeloid leukaemia and lymphoma cell lines as well as primary CLL and T-cell samples were used. Cells we...

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Veröffentlicht in:	Anticancer research 2009-04, Vol.29 (4), p.1355-1360
Hauptverfasser:	Ayuk, Francis, Maywald, Nadja, Hannemann, Sandra, Larsen, Ulrike, Zander, Axel, Kröger, Nicolaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - pharmacology Antilymphocyte Serum - pharmacology Apoptosis - drug effects Apoptosis - immunology Biological and medical sciences Cytotoxicity, Immunologic Flow Cytometry Hematologic Neoplasms - drug therapy Hematologic Neoplasms - immunology Hematologic Neoplasms - therapy Humans Immunoglobulins - pharmacology Medical sciences T-Lymphocytes - immunology Tumors
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