Long-term antibody response and immunologic memory in children immunized with hepatitis B vaccine at birth
Four hundred and fifty three healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 10-11 years of age for persistence of anti-hepatitis B-S antigen antibody (anti-HBs); and responses of children without protective antibody to different doses of hepatitis B...
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| Veröffentlicht in: | Indian pediatrics 2004-12, Vol.41 (12), p.1232-1237 |
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| creator | SAFFAR, M. J REZAI, M. S |
| description | Four hundred and fifty three healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 10-11 years of age for persistence of anti-hepatitis B-S antigen antibody (anti-HBs); and responses of children without protective antibody to different doses of hepatitis B vaccine booster were evaluated. Although nearly 42% of them were not seroprotected, but most of boosted subjects (87.3%) retained robust immunologic memory and rapidly retained a protective anti-HBs antibody titer of at least 10 IU/L after booster vaccination. |
| format | Article |
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J ; REZAI, M. S</creator><creatorcontrib>SAFFAR, M. J ; REZAI, M. S</creatorcontrib><description>Four hundred and fifty three healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 10-11 years of age for persistence of anti-hepatitis B-S antigen antibody (anti-HBs); and responses of children without protective antibody to different doses of hepatitis B vaccine booster were evaluated. Although nearly 42% of them were not seroprotected, but most of boosted subjects (87.3%) retained robust immunologic memory and rapidly retained a protective anti-HBs antibody titer of at least 10 IU/L after booster vaccination.</description><identifier>ISSN: 0019-6061</identifier><identifier>PMID: 15623904</identifier><identifier>CODEN: INPDAR</identifier><language>eng</language><publisher>New Delhi: Indian Pediatrics</publisher><subject>Antibody Formation ; Biological and medical sciences ; Child ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; General aspects ; Hepatitis B - prevention & control ; Hepatitis B Vaccines - therapeutic use ; Humans ; Immunization, Secondary ; Immunologic Memory ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Male ; Medical sciences ; Other diseases. 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S</creatorcontrib><title>Long-term antibody response and immunologic memory in children immunized with hepatitis B vaccine at birth</title><title>Indian pediatrics</title><addtitle>Indian Pediatr</addtitle><description>Four hundred and fifty three healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 10-11 years of age for persistence of anti-hepatitis B-S antigen antibody (anti-HBs); and responses of children without protective antibody to different doses of hepatitis B vaccine booster were evaluated. Although nearly 42% of them were not seroprotected, but most of boosted subjects (87.3%) retained robust immunologic memory and rapidly retained a protective anti-HBs antibody titer of at least 10 IU/L after booster vaccination.</description><subject>Antibody Formation</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>General aspects</subject><subject>Hepatitis B - prevention & control</subject><subject>Hepatitis B Vaccines - therapeutic use</subject><subject>Humans</subject><subject>Immunization, Secondary</subject><subject>Immunologic Memory</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other diseases. 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Abdomen</topic><topic>General aspects</topic><topic>Hepatitis B - prevention & control</topic><topic>Hepatitis B Vaccines - therapeutic use</topic><topic>Humans</topic><topic>Immunization, Secondary</topic><topic>Immunologic Memory</topic><topic>Liver. Biliary tract. Portal circulation. Exocrine pancreas</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SAFFAR, M. J</creatorcontrib><creatorcontrib>REZAI, M. 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S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term antibody response and immunologic memory in children immunized with hepatitis B vaccine at birth</atitle><jtitle>Indian pediatrics</jtitle><addtitle>Indian Pediatr</addtitle><date>2004-12</date><risdate>2004</risdate><volume>41</volume><issue>12</issue><spage>1232</spage><epage>1237</epage><pages>1232-1237</pages><issn>0019-6061</issn><coden>INPDAR</coden><abstract>Four hundred and fifty three healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 10-11 years of age for persistence of anti-hepatitis B-S antigen antibody (anti-HBs); and responses of children without protective antibody to different doses of hepatitis B vaccine booster were evaluated. Although nearly 42% of them were not seroprotected, but most of boosted subjects (87.3%) retained robust immunologic memory and rapidly retained a protective anti-HBs antibody titer of at least 10 IU/L after booster vaccination.</abstract><cop>New Delhi</cop><pub>Indian Pediatrics</pub><pmid>15623904</pmid><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Indian pediatrics, 2004-12, Vol.41 (12), p.1232-1237 |
| issn | 0019-6061 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Antibody Formation Biological and medical sciences Child Female Gastroenterology. Liver. Pancreas. Abdomen General aspects Hepatitis B - prevention & control Hepatitis B Vaccines - therapeutic use Humans Immunization, Secondary Immunologic Memory Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Other diseases. Semiology Time Factors |
| title | Long-term antibody response and immunologic memory in children immunized with hepatitis B vaccine at birth |
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