Bioavailability of 2- O -α- d -glucopyranosyl- l -ascorbic acid as ascorbic acid in healthy humans

Abstract Objective 2- O -α- d -glucopyranosyl-L-ascorbic acid (AA2G) is a stable glycoside, but its conversion to bioavailable ascorbic acid (AsA) in humans remains unknown. The aim of this study was to clarify that AA2G is hydrolyzed by human intestinal maltase and AA2G by oral ingestion is physiol...

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Veröffentlicht in:	Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2009-06, Vol.25 (6), p.686-691
Hauptverfasser:	Nakamura, Sadako, Ph.D, Oku, Tsuneyuki, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	2- O-α- d-glucopyranosyl-L-ascorbic acid AA2G administered dose alpha-glucosidase alpha-Glucosidases - metabolism animal models Animals Area Under Curve Ascorbic acid Ascorbic Acid - analogs & derivatives Ascorbic Acid - pharmacokinetics Bioavailability in humans Biological and medical sciences Biological Availability blood serum Chromatography, High Pressure Liquid dose response Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gastroenterology and Hepatology glycosides health foods Humans Hydrolysis intestinal absorption Intestinal maltase Intestinal Mucosa - enzymology nutrient availability Rats Species Specificity Vertebrates: anatomy and physiology, studies on body, several organs or systems vitamin metabolism vitamin supplements women Young Adult
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