Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus

Abstract Epicatechin gallate (1) and epigallocatechin gallate (2) were evaluated for their antibacterial and efflux inhibitory activity against a wild-type and three multidrug-resistant (MDR) strains of STAPHYLOCOCCUS AUREUS. Compound 2 was more active than 1 based on minimum inhibitory concentratio...

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Veröffentlicht in:	Planta medica 2004-12, Vol.70 (12), p.1240-1242
Hauptverfasser:	Gibbons, S, Moser, E, Kaatz, G.W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use antibacterial properties Biological and medical sciences catechin Catechin - administration & dosage Catechin - analogs & derivatives Catechin - pharmacology Catechin - therapeutic use chemical structure Drug Resistance, Multiple epicatechin epigallocatechin General pharmacology Humans Letter Medical sciences Microbial Sensitivity Tests multiple drug resistance Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plants, Medicinal Staphylococcus aureus Staphylococcus aureus - drug effects
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