Role of cytokines in anaphylactoid reaction with marked eosinophilia in a hemodialysis patient
Hemodialysis is rarely terminated by events associated with anticoagulants. A 69-year-old woman on hemodialysis due to chronic renal failure (CRF) developed an anaphylactoid reaction with hypereosinophilia. On the basis of clinical and laboratory findings, we concluded that the causes of this anaphy...
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Veröffentlicht in: | Clinical and experimental nephrology 2004-12, Vol.8 (4), p.384-387 |
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creator | Kanda, Eiichiro Kida, Yujiro Suzuki, Hitoe Ando, Minoru Nihei, Hiroshi Sasaki, Sei Saito, Hiroshi |
description | Hemodialysis is rarely terminated by events associated with anticoagulants. A 69-year-old woman on hemodialysis due to chronic renal failure (CRF) developed an anaphylactoid reaction with hypereosinophilia. On the basis of clinical and laboratory findings, we concluded that the causes of this anaphylactoid reaction were low-molecular-weight heparin and heparin. Our patient also showed high levels of soluble interleukin-2 receptor (sIL-2R) and eosinophil cationic protein (ECP), which decreased after the cessation of hemo-dialysis. To date, there has been no report of high levels of cytokines induced by hemodialysis-associated anaphylactoid reaction. In this report, we discuss the mechanism underlying drug-induced anaphylactoid reaction, particularly that involving eosinophilia and cytokines. |
doi_str_mv | 10.1007/s10157-004-0300-4 |
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A 69-year-old woman on hemodialysis due to chronic renal failure (CRF) developed an anaphylactoid reaction with hypereosinophilia. On the basis of clinical and laboratory findings, we concluded that the causes of this anaphylactoid reaction were low-molecular-weight heparin and heparin. Our patient also showed high levels of soluble interleukin-2 receptor (sIL-2R) and eosinophil cationic protein (ECP), which decreased after the cessation of hemo-dialysis. To date, there has been no report of high levels of cytokines induced by hemodialysis-associated anaphylactoid reaction. 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A 69-year-old woman on hemodialysis due to chronic renal failure (CRF) developed an anaphylactoid reaction with hypereosinophilia. On the basis of clinical and laboratory findings, we concluded that the causes of this anaphylactoid reaction were low-molecular-weight heparin and heparin. Our patient also showed high levels of soluble interleukin-2 receptor (sIL-2R) and eosinophil cationic protein (ECP), which decreased after the cessation of hemo-dialysis. To date, there has been no report of high levels of cytokines induced by hemodialysis-associated anaphylactoid reaction. 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A 69-year-old woman on hemodialysis due to chronic renal failure (CRF) developed an anaphylactoid reaction with hypereosinophilia. On the basis of clinical and laboratory findings, we concluded that the causes of this anaphylactoid reaction were low-molecular-weight heparin and heparin. Our patient also showed high levels of soluble interleukin-2 receptor (sIL-2R) and eosinophil cationic protein (ECP), which decreased after the cessation of hemo-dialysis. To date, there has been no report of high levels of cytokines induced by hemodialysis-associated anaphylactoid reaction. In this report, we discuss the mechanism underlying drug-induced anaphylactoid reaction, particularly that involving eosinophilia and cytokines.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>15619042</pmid><doi>10.1007/s10157-004-0300-4</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Anaphylaxis - blood Anaphylaxis - etiology Anaphylaxis - immunology Cytokines - blood Cytokines - immunology Eosinophil Cationic Protein - blood Eosinophilia - immunology Female Heparin - immunology Humans Kidney Failure, Chronic - therapy Receptors, Interleukin-2 - blood Renal Dialysis - adverse effects |
title | Role of cytokines in anaphylactoid reaction with marked eosinophilia in a hemodialysis patient |
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