Acyl Coenzyme A Synthetase Regulation: Putative Role in Long‐Chain Acyl Coenzyme A Partitioning

Objective: Long‐chain acyl coenzyme A synthetase (ACSL) converts free fatty acids (FFAs) into their metabolizable long‐chain acyl coenzyme A (LC‐CoA) derivatives that are essential for FFA conversion to CO2, triglycerides, or complex lipids. ACSL‐1 is highly expressed in adipose tissue with broad su...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2004-11, Vol.12 (11), p.1781-1788
Hauptverfasser:	Wang, Yan‐Lin, Guo, Wen, Zang, Yan, Yaney, Gordon C., Vallega, Gino, Getty‐Kaushik, Lisa, Pilch, Paul, Kandror, Konstantin, Corkey, Barbara E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Coenzyme A - metabolism adipocytes Adipocytes - enzymology Adipocytes - ultrastructure Aging Animals Cell Fractionation Cell Membrane - enzymology Cell Nucleus - enzymology Coenzyme A Ligases - analysis Coenzyme A Ligases - metabolism Diabetes Mellitus, Experimental - enzymology Fasting fatty acid metabolism Fatty Acids, Nonesterified - metabolism Homeostasis insulin Insulin - pharmacology Lipids - biosynthesis Male metabolic regulation Microsomes - enzymology Mitochondria - enzymology Oxidation-Reduction partitioning Rats Rats, Sprague-Dawley
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