Dedifferentiated liposarcoma of the cheek

Liposarcomas of the head and neck region are rare; only a few cases have been reported to arise in the cheek or buccal mucosa. Dedifferentiated liposarcoma has rarely been reported in the head and neck region and, to the best of our knowledge, this is the first reported case of dedifferentiated lipo...

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Veröffentlicht in:Annals of diagnostic pathology 2004-12, Vol.8 (6), p.352-357
Hauptverfasser: de la Roza, Gustavo, Baredes, Soly, Aisner, Seena C.
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container_title Annals of diagnostic pathology
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creator de la Roza, Gustavo
Baredes, Soly
Aisner, Seena C.
description Liposarcomas of the head and neck region are rare; only a few cases have been reported to arise in the cheek or buccal mucosa. Dedifferentiated liposarcoma has rarely been reported in the head and neck region and, to the best of our knowledge, this is the first reported case of dedifferentiated liposarcoma of the cheek. Dedifferentiated liposarcoma is a mixed histologic subtype defined by the association of an atypical lipomatous tumor or well-differentiated liposarcoma and a nonlipogenic sarcoma. The patient was a 61-year-old man who presented with a soft-tissue mass of the left cheek and a presumptive diagnosis of salivary neoplasm based on a fine needle aspiration. The tumor was excised and consisted histologically of an atypical lipomatous tumor/well-differentiated liposarcoma composed a well-differentiated lipomatous neoplasm with atypical cells and rare lipoblasts. The tumor recurred in the same location 5 months after surgery. The recurrent tumor was primarily composed of a nonlipogenic spindle sarcoma with focal rhabdomyoblastic differentiation associated with areas of an atypical lipomatous tumor/well-differentiated liposarcoma.
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Dedifferentiated liposarcoma has rarely been reported in the head and neck region and, to the best of our knowledge, this is the first reported case of dedifferentiated liposarcoma of the cheek. Dedifferentiated liposarcoma is a mixed histologic subtype defined by the association of an atypical lipomatous tumor or well-differentiated liposarcoma and a nonlipogenic sarcoma. The patient was a 61-year-old man who presented with a soft-tissue mass of the left cheek and a presumptive diagnosis of salivary neoplasm based on a fine needle aspiration. The tumor was excised and consisted histologically of an atypical lipomatous tumor/well-differentiated liposarcoma composed a well-differentiated lipomatous neoplasm with atypical cells and rare lipoblasts. The tumor recurred in the same location 5 months after surgery. 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subjects Biomarkers, Tumor - analysis
Biopsy, Fine-Needle
Cheek - pathology
Cheek - surgery
Dedifferentiated liposarcoma
Diagnosis, Differential
Facial Neoplasms - chemistry
Facial Neoplasms - pathology
Facial Neoplasms - surgery
head & neck
Humans
Immunoenzyme Techniques
Liposarcoma - chemistry
Liposarcoma - pathology
Liposarcoma - surgery
Male
Middle Aged
Neoplasm Recurrence, Local
Salivary Gland Neoplasms - pathology
Treatment Outcome
title Dedifferentiated liposarcoma of the cheek
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