An In Vivo Model of Wound Healing in Genetically Modified Skin-Humanized Mice

Cutaneous wound-healing disorders are a major health problem that requires the development of innovative treatments. Whithin this context, the search for reliable human wound-healing models that allow us to address both mechanistic and therapeutic matters is warranted. In this study, we have develop...

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Veröffentlicht in:	Journal of investigative dermatology 2004-12, Vol.123 (6), p.1182-1191
Hauptverfasser:	Escámez, María José, García, Marta, Larcher, Fernando, Meana, Alvaro, Muñoz, Evangelina, Jorcano, Jose Luis, Del Río, Marcela
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Differentiation Cell Division Cells, Cultured Dermatology Dermis - cytology Dermis - injuries Dermis - physiology Disease Models, Animal Epidermis - cytology Epidermis - injuries Epidermis - physiology Extracellular Matrix - physiology Fibroblast Growth Factor 7 Fibroblast Growth Factors - pharmacology gene therapy and humanized models Genetic Therapy Humans Keratinocytes - cytology Keratinocytes - physiology Medical sciences Mice Mice, Nude Regeneration - physiology Skin Transplantation Tissue Engineering wound healing Wound Healing - drug effects Wound Healing - physiology Wounds and Injuries - drug therapy Wounds and Injuries - physiopathology
Online-Zugang:	Volltext
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