Congenital rubella infection following rubella outbreak in northern Italy, 2002: need for an effective vaccination programme
Presented here are the details of a rubella outbreak that occurred in 2002 in the Lombardy region of northern Italy followed by a discussion of rubella vaccination policy in this country. From 13 maternal cases of rubella infection, congenital rubella infection was diagnosed in three fetuses and thr...
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| Veröffentlicht in: | European journal of clinical microbiology & infectious diseases 2004-10, Vol.23 (10), p.780-783 |
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| creator | REVELLO, M. G GORINI, G ZAVATTONI, M FURIONE, M GERNA, G |
| description | Presented here are the details of a rubella outbreak that occurred in 2002 in the Lombardy region of northern Italy followed by a discussion of rubella vaccination policy in this country. From 13 maternal cases of rubella infection, congenital rubella infection was diagnosed in three fetuses and three newborns. Of the three infected fetuses, one was aborted and two died in utero, while of the three infected newborns, two were born with severe disease and one was subclinically infected. Follow-up revealed that one of the two symptomatic newborns had died at 4 months of age with disseminated rubella infection, while the other suffered from bilateral blindness and deafness and was severely retarded at 15 months of age. The remaining infant remained asymptomatic at 14 months. Congenital rubella remains a serious health problem in Italy and a successful vaccination strategy is required. |
| doi_str_mv | 10.1007/s10096-004-1213-6 |
| format | Article |
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G ; GORINI, G ; ZAVATTONI, M ; FURIONE, M ; GERNA, G</creator><creatorcontrib>REVELLO, M. G ; GORINI, G ; ZAVATTONI, M ; FURIONE, M ; GERNA, G</creatorcontrib><description>Presented here are the details of a rubella outbreak that occurred in 2002 in the Lombardy region of northern Italy followed by a discussion of rubella vaccination policy in this country. From 13 maternal cases of rubella infection, congenital rubella infection was diagnosed in three fetuses and three newborns. Of the three infected fetuses, one was aborted and two died in utero, while of the three infected newborns, two were born with severe disease and one was subclinically infected. Follow-up revealed that one of the two symptomatic newborns had died at 4 months of age with disseminated rubella infection, while the other suffered from bilateral blindness and deafness and was severely retarded at 15 months of age. The remaining infant remained asymptomatic at 14 months. Congenital rubella remains a serious health problem in Italy and a successful vaccination strategy is required.</description><identifier>ISSN: 0934-9723</identifier><identifier>EISSN: 1435-4373</identifier><identifier>DOI: 10.1007/s10096-004-1213-6</identifier><identifier>PMID: 15368099</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adult ; Biological and medical sciences ; Disease Outbreaks ; Female ; Human viral diseases ; Humans ; Immunization Programs ; Infectious diseases ; Italy - epidemiology ; Medical sciences ; Outbreaks ; Pregnancy ; Pregnancy Complications, Infectious - epidemiology ; Rubella - epidemiology ; Rubella Syndrome, Congenital - epidemiology ; Rubella Syndrome, Congenital - prevention & control ; Vaccination ; Vaccines ; Viral diseases ; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><ispartof>European journal of clinical microbiology & infectious diseases, 2004-10, Vol.23 (10), p.780-783</ispartof><rights>2004 INIST-CNRS</rights><rights>Springer-Verlag 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-bce7a370a11460e63b15f9719692fdcfbce0e1aa40400ad2644471f12f10923b3</citedby><cites>FETCH-LOGICAL-c385t-bce7a370a11460e63b15f9719692fdcfbce0e1aa40400ad2644471f12f10923b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27913,27914</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16202625$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15368099$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>REVELLO, M. 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Follow-up revealed that one of the two symptomatic newborns had died at 4 months of age with disseminated rubella infection, while the other suffered from bilateral blindness and deafness and was severely retarded at 15 months of age. The remaining infant remained asymptomatic at 14 months. 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| subjects | Adult Biological and medical sciences Disease Outbreaks Female Human viral diseases Humans Immunization Programs Infectious diseases Italy - epidemiology Medical sciences Outbreaks Pregnancy Pregnancy Complications, Infectious - epidemiology Rubella - epidemiology Rubella Syndrome, Congenital - epidemiology Rubella Syndrome, Congenital - prevention & control Vaccination Vaccines Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye |
| title | Congenital rubella infection following rubella outbreak in northern Italy, 2002: need for an effective vaccination programme |
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