Prediction of TP53 Status for Primary Cisplatin, Fluorouracil, and Leucovorin Chemotherapy in Ethmoid Sinus Intestinal-Type Adenocarcinoma

To assess the role of TP53 status in predicting pathologic complete remission after primary chemotherapy in patients with ethmoidal intestinal-type adenocarcinoma (ITAC). Thirty patients with ethmoidal ITAC enrolled onto a phase II study received chemotherapy with cisplatin, fluorouracil, and leucov...

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Veröffentlicht in:	Journal of clinical oncology 2004-12, Vol.22 (24), p.4901-4906
Hauptverfasser:	LICITRA, L, SUARDI, S, PIEROTTI, M. A, PILOTTI, S, BOSSI, P, LOCATI, L. D, MARIANI, L, QUATTRONE, P, LO VULLO, S, OGGIONNI, M, OLMI, P, CANTA, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - genetics Adenocarcinoma - radiotherapy Adenocarcinoma - surgery Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Cisplatin - administration & dosage Combined Modality Therapy DNA Mutational Analysis Ethmoid Sinus - pathology Female Fluorouracil - administration & dosage Forecasting Humans Infusions, Intravenous Leucovorin - administration & dosage Male Medical sciences Middle Aged Paranasal Sinus Neoplasms - drug therapy Paranasal Sinus Neoplasms - genetics Paranasal Sinus Neoplasms - radiotherapy Paranasal Sinus Neoplasms - surgery Predictive Value of Tests Prognosis Prospective Studies Treatment Outcome Tumor Suppressor Protein p53 - analysis Tumor Suppressor Protein p53 - genetics Tumors
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