Association of a Common Variant of the CASP8 Gene With Reduced Risk of Breast Cancer

Apoptosis, or programmed cell death, is perturbed in many cancers. We tested the hypothesis that coding polymorphisms of the death receptor 4 (DR4), caspase-8 (CASP8), and caspase-10 (CASP10) genes might act as low-penetrance breast cancer genes. Single-nucleotide polymorphisms (SNPs) of these genes...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2004-12, Vol.96 (24), p.1866-1869
Hauptverfasser:	MacPherson, Gordon, Healey, Catherine S., Teare, M. Dawn, Balasubramanian, Sabapathy P., Reed, Malcolm W. R., Pharoah, Paul D. P., Ponder, Bruce A. J., Meuth, Mark, Bhattacharyya, Nitai P., Cox, Angela
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspartic Acid Biological and medical sciences Breast cancer Breast Neoplasms - genetics Case-Control Studies Caspase 10 Caspase 8 Caspases - genetics England Female Genes Genetic Predisposition to Disease Genetic Variation Gynecology. Andrology. Obstetrics Heterozygote Histidine Homozygote Humans Mammary gland diseases Medical research Medical sciences Odds Ratio Polymorphism, Single Nucleotide Receptors, TNF-Related Apoptosis-Inducing Ligand Receptors, Tumor Necrosis Factor - genetics Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!