Characterization and application of the selective strand annealing activity of the N terminal domain of hepatitis delta antigen

We used synthetic DNA oligos to investigate the nucleic acid chaperone properties of the N terminal domain of hepatitis delta antigen (NdAg). We found that NdAg possessed a bona fide chaperone activity. NdAg could distinguish subtle differences in the thermal stability of the base pairing region, an...

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Veröffentlicht in:	FEBS letters 2004-12, Vol.578 (3), p.345-350
Hauptverfasser:	Huang, Zhi-Shun, Chen, Albert You-Ju, Wu, Huey-Nan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Pairing Base Sequence Escherichia coli - genetics Hepatitis delta antigen Hepatitis delta Antigens - chemistry Hepatitis delta Antigens - genetics Hepatitis delta Antigens - metabolism Hepatitis Delta Virus - genetics Hepatitis Delta Virus - metabolism Hybridization Immunoblotting In Situ Hybridization Molecular Chaperones - chemistry Molecular Chaperones - metabolism Molecular Sequence Data Nucleic acid chaperone Protein Structure, Tertiary Strand annealing
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