Suction Blister Epidermal Grafts Combined with CO2 Laser Superficial Ablation as a Good Method for Treating Small‐Sized Vitiligo

BACKGROUND Despite the availability of various new methods to treat vitiligo, surgical methods offer rapid, simple, and safe ways for treating small‐sized vitiligo. OBJECTIVE To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with C...

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Veröffentlicht in:Dermatologic surgery 2009-04, Vol.35 (4), p.601-606
Hauptverfasser: KO, WANG‐CHENG, CHEN, YU‐FU
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CHEN, YU‐FU
description BACKGROUND Despite the availability of various new methods to treat vitiligo, surgical methods offer rapid, simple, and safe ways for treating small‐sized vitiligo. OBJECTIVE To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with CO2 laser epidermal ablation. METHODS Forty patients with small, stable vitiligo were treated using SBEG combined with CO2 laser epidermal ablation and followed up for at least 6 months and up to 10 years. RESULTS Treatment outcomes were excellent for 32 patients (80%), good for four patients (10%), fair for three patients (7.5%), and poor for one patient (2.5%). No scar formation was observed in any patients. Location of the lesions was probably the most important factor in determining the outcomes of transplantation. CONCLUSION This study suggests that SBEG combined with CO2 laser ablation is a rapid, simple, and safe method to treat vitiligo, especially for patients with small and stable vitiliginous lesions.
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OBJECTIVE To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with CO2 laser epidermal ablation. METHODS Forty patients with small, stable vitiligo were treated using SBEG combined with CO2 laser epidermal ablation and followed up for at least 6 months and up to 10 years. RESULTS Treatment outcomes were excellent for 32 patients (80%), good for four patients (10%), fair for three patients (7.5%), and poor for one patient (2.5%). No scar formation was observed in any patients. Location of the lesions was probably the most important factor in determining the outcomes of transplantation. CONCLUSION This study suggests that SBEG combined with CO2 laser ablation is a rapid, simple, and safe method to treat vitiligo, especially for patients with small and stable vitiliginous lesions.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1111/j.1524-4725.2009.01098.x</identifier><identifier>PMID: 19400882</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Blister ; Bullous diseases of the skin ; Child ; Dermatology ; Epidermis ; Feasibility Studies ; Female ; Humans ; Laser Therapy - instrumentation ; Lasers, Gas ; Male ; Medical sciences ; Middle Aged ; Pigmentary diseases of the skin ; Skin plastic surgery ; Skin Transplantation ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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OBJECTIVE To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with CO2 laser epidermal ablation. METHODS Forty patients with small, stable vitiligo were treated using SBEG combined with CO2 laser epidermal ablation and followed up for at least 6 months and up to 10 years. RESULTS Treatment outcomes were excellent for 32 patients (80%), good for four patients (10%), fair for three patients (7.5%), and poor for one patient (2.5%). No scar formation was observed in any patients. Location of the lesions was probably the most important factor in determining the outcomes of transplantation. CONCLUSION This study suggests that SBEG combined with CO2 laser ablation is a rapid, simple, and safe method to treat vitiligo, especially for patients with small and stable vitiliginous lesions.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Blister</subject><subject>Bullous diseases of the skin</subject><subject>Child</subject><subject>Dermatology</subject><subject>Epidermis</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Laser Therapy - instrumentation</subject><subject>Lasers, Gas</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pigmentary diseases of the skin</subject><subject>Skin plastic surgery</subject><subject>Skin Transplantation</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Treatment Outcome</subject><subject>Vitiligo - radiotherapy</subject><subject>Vitiligo - surgery</subject><subject>Young Adult</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFu1DAURSMEoqXwC8gb2CU8O06cLFiUaRmQBnWRlq3l2E7HgxMPdqJpWSG-gG_kS3A6UdliyfKT3rn32ddJgjBkOK53uwwXhKaUkSIjAHUGGOoqu3uSnD42nsYaWJlCgclJ8iKEHQAmdQ7PkxNcU4CqIqfJr2aSo3ED-mBNGLVHl3ujtO-FRWsvujGgletbM2iFDmbcotUVQRsRIthMe-07I01Ez1srHlxEQAKtnVPoix638eicR9dex-5wi5poa__8_N2YH9HvqxmNNbfuZfKsEzboV8t5ltx8vLxefUo3V-vPq_NNKiklRVrLVte61LIUZcXaVrACxwcpmlOsVasokbLMRVfgsuoUY2Ur65owSasOCiAqP0veHn333n2fdBh5b4LU1opBuynwkmFWkIpFsDqC0rsQvO743pte-HuOgc_58x2fY-ZzzHzOnz_kz--i9PUyY2p7rf4Jl8Aj8GYBRJDCdl4M0oRHjuCclQTjyNEjd3A2fkv4ZqeD9nyrhR23HAAoYaRK5-EQrSGNG4ooe7_IjNX3_31vftHczFX-F_M2sfw</recordid><startdate>200904</startdate><enddate>200904</enddate><creator>KO, WANG‐CHENG</creator><creator>CHEN, YU‐FU</creator><general>Blackwell Publishing Inc</general><general>by the American Society for Dermatologic Surgery, Inc</general><general>Wiley</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200904</creationdate><title>Suction Blister Epidermal Grafts Combined with CO2 Laser Superficial Ablation as a Good Method for Treating Small‐Sized Vitiligo</title><author>KO, WANG‐CHENG ; CHEN, YU‐FU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4425-9cbe9e6ec6a687bba751012d4341edbd42cc63af5168fd776bc9927c48f0502d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Blister</topic><topic>Bullous diseases of the skin</topic><topic>Child</topic><topic>Dermatology</topic><topic>Epidermis</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Laser Therapy - instrumentation</topic><topic>Lasers, Gas</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pigmentary diseases of the skin</topic><topic>Skin plastic surgery</topic><topic>Skin Transplantation</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Treatment Outcome</topic><topic>Vitiligo - radiotherapy</topic><topic>Vitiligo - surgery</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KO, WANG‐CHENG</creatorcontrib><creatorcontrib>CHEN, YU‐FU</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KO, WANG‐CHENG</au><au>CHEN, YU‐FU</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suction Blister Epidermal Grafts Combined with CO2 Laser Superficial Ablation as a Good Method for Treating Small‐Sized Vitiligo</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2009-04</date><risdate>2009</risdate><volume>35</volume><issue>4</issue><spage>601</spage><epage>606</epage><pages>601-606</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>BACKGROUND Despite the availability of various new methods to treat vitiligo, surgical methods offer rapid, simple, and safe ways for treating small‐sized vitiligo. OBJECTIVE To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with CO2 laser epidermal ablation. METHODS Forty patients with small, stable vitiligo were treated using SBEG combined with CO2 laser epidermal ablation and followed up for at least 6 months and up to 10 years. RESULTS Treatment outcomes were excellent for 32 patients (80%), good for four patients (10%), fair for three patients (7.5%), and poor for one patient (2.5%). No scar formation was observed in any patients. Location of the lesions was probably the most important factor in determining the outcomes of transplantation. CONCLUSION This study suggests that SBEG combined with CO2 laser ablation is a rapid, simple, and safe method to treat vitiligo, especially for patients with small and stable vitiliginous lesions.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>19400882</pmid><doi>10.1111/j.1524-4725.2009.01098.x</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Journals@Ovid Complete
subjects Adolescent
Adult
Biological and medical sciences
Blister
Bullous diseases of the skin
Child
Dermatology
Epidermis
Feasibility Studies
Female
Humans
Laser Therapy - instrumentation
Lasers, Gas
Male
Medical sciences
Middle Aged
Pigmentary diseases of the skin
Skin plastic surgery
Skin Transplantation
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Treatment Outcome
Vitiligo - radiotherapy
Vitiligo - surgery
Young Adult
title Suction Blister Epidermal Grafts Combined with CO2 Laser Superficial Ablation as a Good Method for Treating Small‐Sized Vitiligo
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