Comparative effects of the antipsychotics sulpiride and risperidone in female rats on energy balance, body composition, fat morphology and macronutrient selection

Previous studies showed that the antipsychotic drugs (APDs) sulpiride (SUL) and risperidone (RIS) induced body weight gain (BWG), hyperphagia, and increased serum levels of leptin, prolactin and corticosterone in female rats. Neither SUL nor RIS increased BWG or food intake (FI) in male rats. To fur...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2004-12, Vol.28 (8), p.1305-1311
Hauptverfasser:	Baptista, Trino, de Baptista, Emma Araujo, Lalonde, Josee, Plamondon, Julie, Kin, N.M.K. Ng Ying, Beaulieu, Serge, Joober, Rhida, Richard, Denis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - drug effects Adipose Tissue - drug effects Animal model Animals Antipsychotic Agents - pharmacology Antipsychotic drugs Body Composition - drug effects Body Weight - drug effects Cell Count - methods Corticosterone - blood Dietary Fats - metabolism Eating - drug effects Energy Metabolism - drug effects Female Hyperplasic obesity Hyperthropic obesity Leptin - blood Macronutrient intake Obesity Prolactin - blood Proteins - metabolism Rats Rats, Wistar Risperidone - pharmacology Sulpiride - pharmacology
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