Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease

To examine the influence of the APOE genotype on levels of beta-amyloid (Abeta) plaque load and atrophy in patients with Alzheimer disease (AD) in vivo. Thirty-two patients with moderate AD were divided into carriers and noncarriers of the epsilon4 allele. These groups were matched for age, disease...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurology 2009-04, Vol.72 (17), p.1487-1494
Hauptverfasser:	Drzezga, A, Grimmer, T, Henriksen, G, Mühlau, M, Perneczky, R, Miederer, I, Praus, C, Sorg, C, Wohlschläger, A, Riemenschneider, M, Wester, H J, Foerstl, H, Schwaiger, M, Kurz, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - diagnostic imaging Alzheimer Disease - genetics Alzheimer Disease - pathology Amyloid beta-Peptides - metabolism Apolipoprotein E4 - genetics Apolipoproteins E - genetics Benzothiazoles Brain - diagnostic imaging Brain - metabolism Brain - pathology Carbon Radioisotopes DNA Mutational Analysis Female Gene Frequency - genetics Genetic Predisposition to Disease - genetics Genetic Testing Genotype Humans Male Middle Aged Plaque, Amyloid - metabolism Plaque, Amyloid - pathology Polymorphism, Genetic - genetics Positron-Emission Tomography Risk Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!