Three successful pregnancies following natural conception over an 8-year time span despite serum follicle stimulating hormone level greater than 15 mIU/ml
To demonstrate that the concept that a level of serum follicle stimulating hormone (FSH) of > 15 mIU/ml on day 3 of a younger woman's menstrual cycle suggests that the remaining eggs are of very poor quality consistent with a woman of very advanced reproductive age is a fallacy. A woman with...
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Veröffentlicht in: | Clinical and experimental obstetrics & gynecology 2009, Vol.36 (1), p.12-14 |
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creator | Check, J H Giangreco, J |
description | To demonstrate that the concept that a level of serum follicle stimulating hormone (FSH) of > 15 mIU/ml on day 3 of a younger woman's menstrual cycle suggests that the remaining eggs are of very poor quality consistent with a woman of very advanced reproductive age is a fallacy.
A woman with a serum FSH > 15 mIU/ml on day 3 was studied over an 8-year time period.
Despite the absence of therapy with follicle maturing drugs, and at the latter part of the study the development of oligomenorrhea, the woman had three successful conceptions over eight years without ART techniques. Though two of her pregnancies were treated with progesterone starting in the luteal phase, her last pregnancy was without any treatment.
The policy of certain physicians to advise couples that their eggs are extremely unlikely to develop into a normal pregnancy because of increased day 3 serum FSH and that they should immediately proceed to using donor oocytes (even if that is not their desire) is wrong. These women should be given an attempt to achieve a pregnancy with their own eggs. However, the treating physician should avoid the use of high-dosage follicle maturing drugs. |
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A woman with a serum FSH > 15 mIU/ml on day 3 was studied over an 8-year time period.
Despite the absence of therapy with follicle maturing drugs, and at the latter part of the study the development of oligomenorrhea, the woman had three successful conceptions over eight years without ART techniques. Though two of her pregnancies were treated with progesterone starting in the luteal phase, her last pregnancy was without any treatment.
The policy of certain physicians to advise couples that their eggs are extremely unlikely to develop into a normal pregnancy because of increased day 3 serum FSH and that they should immediately proceed to using donor oocytes (even if that is not their desire) is wrong. These women should be given an attempt to achieve a pregnancy with their own eggs. However, the treating physician should avoid the use of high-dosage follicle maturing drugs.</description><identifier>ISSN: 0390-6663</identifier><identifier>PMID: 19405209</identifier><language>eng</language><publisher>Canada</publisher><subject>Abortion, Spontaneous ; Adult ; Female ; Fertilization - physiology ; Follicle Stimulating Hormone - blood ; Humans ; Oocytes - physiology ; Ovulation - physiology ; Pregnancy ; Progesterone - therapeutic use ; Progestins - therapeutic use ; Term Birth</subject><ispartof>Clinical and experimental obstetrics & gynecology, 2009, Vol.36 (1), p.12-14</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,4010</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19405209$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Check, J H</creatorcontrib><creatorcontrib>Giangreco, J</creatorcontrib><title>Three successful pregnancies following natural conception over an 8-year time span despite serum follicle stimulating hormone level greater than 15 mIU/ml</title><title>Clinical and experimental obstetrics & gynecology</title><addtitle>Clin Exp Obstet Gynecol</addtitle><description>To demonstrate that the concept that a level of serum follicle stimulating hormone (FSH) of > 15 mIU/ml on day 3 of a younger woman's menstrual cycle suggests that the remaining eggs are of very poor quality consistent with a woman of very advanced reproductive age is a fallacy.
A woman with a serum FSH > 15 mIU/ml on day 3 was studied over an 8-year time period.
Despite the absence of therapy with follicle maturing drugs, and at the latter part of the study the development of oligomenorrhea, the woman had three successful conceptions over eight years without ART techniques. Though two of her pregnancies were treated with progesterone starting in the luteal phase, her last pregnancy was without any treatment.
The policy of certain physicians to advise couples that their eggs are extremely unlikely to develop into a normal pregnancy because of increased day 3 serum FSH and that they should immediately proceed to using donor oocytes (even if that is not their desire) is wrong. These women should be given an attempt to achieve a pregnancy with their own eggs. However, the treating physician should avoid the use of high-dosage follicle maturing drugs.</description><subject>Abortion, Spontaneous</subject><subject>Adult</subject><subject>Female</subject><subject>Fertilization - physiology</subject><subject>Follicle Stimulating Hormone - blood</subject><subject>Humans</subject><subject>Oocytes - physiology</subject><subject>Ovulation - physiology</subject><subject>Pregnancy</subject><subject>Progesterone - therapeutic use</subject><subject>Progestins - therapeutic use</subject><subject>Term Birth</subject><issn>0390-6663</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kMtOwzAQRbMA0VL4BeQVuwi7Tux2iSoelSqxadeR7UxaIz-CH0X9Fb4WA2U1uqMzR5p7UU0xXeKaMUYn1XWM7xg3DWfkqpqQZYPbOV5Oq6_tIQCgmJWCGIds0Bhg74RTGiIavDH-U7s9ciLlIAxS3ikYk_YO-SMEJBxa1CcQASVti2csix7iqFMJELL9dWhlSixENiL96A4-WO8AGTiCQfsAIhVZOpRr0iK73j1Yc1NdDsJEuD3PWbV7ftquXuvN28t69bipx_JBqqVcgiR4QRsFLSeYtBQ3ihHVwkCUUBLPpWCMMwqECtkw2dOG02beMy5Iz-msuv_zjsF_ZIipszoqMEY48Dl2jBNOF5QW8O4MZmmh78agrQin7r9N-g07nHMm</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Check, J H</creator><creator>Giangreco, J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>Three successful pregnancies following natural conception over an 8-year time span despite serum follicle stimulating hormone level greater than 15 mIU/ml</title><author>Check, J H ; Giangreco, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-bb9eb10834ce571015304c61c5ef1cacb02ba66763e13ab46bd347342d67a1d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Abortion, Spontaneous</topic><topic>Adult</topic><topic>Female</topic><topic>Fertilization - physiology</topic><topic>Follicle Stimulating Hormone - blood</topic><topic>Humans</topic><topic>Oocytes - physiology</topic><topic>Ovulation - physiology</topic><topic>Pregnancy</topic><topic>Progesterone - therapeutic use</topic><topic>Progestins - therapeutic use</topic><topic>Term Birth</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Check, J H</creatorcontrib><creatorcontrib>Giangreco, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental obstetrics & gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Check, J H</au><au>Giangreco, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Three successful pregnancies following natural conception over an 8-year time span despite serum follicle stimulating hormone level greater than 15 mIU/ml</atitle><jtitle>Clinical and experimental obstetrics & gynecology</jtitle><addtitle>Clin Exp Obstet Gynecol</addtitle><date>2009</date><risdate>2009</risdate><volume>36</volume><issue>1</issue><spage>12</spage><epage>14</epage><pages>12-14</pages><issn>0390-6663</issn><abstract>To demonstrate that the concept that a level of serum follicle stimulating hormone (FSH) of > 15 mIU/ml on day 3 of a younger woman's menstrual cycle suggests that the remaining eggs are of very poor quality consistent with a woman of very advanced reproductive age is a fallacy.
A woman with a serum FSH > 15 mIU/ml on day 3 was studied over an 8-year time period.
Despite the absence of therapy with follicle maturing drugs, and at the latter part of the study the development of oligomenorrhea, the woman had three successful conceptions over eight years without ART techniques. Though two of her pregnancies were treated with progesterone starting in the luteal phase, her last pregnancy was without any treatment.
The policy of certain physicians to advise couples that their eggs are extremely unlikely to develop into a normal pregnancy because of increased day 3 serum FSH and that they should immediately proceed to using donor oocytes (even if that is not their desire) is wrong. These women should be given an attempt to achieve a pregnancy with their own eggs. However, the treating physician should avoid the use of high-dosage follicle maturing drugs.</abstract><cop>Canada</cop><pmid>19405209</pmid><tpages>3</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Abortion, Spontaneous Adult Female Fertilization - physiology Follicle Stimulating Hormone - blood Humans Oocytes - physiology Ovulation - physiology Pregnancy Progesterone - therapeutic use Progestins - therapeutic use Term Birth |
title | Three successful pregnancies following natural conception over an 8-year time span despite serum follicle stimulating hormone level greater than 15 mIU/ml |
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