Reducing storage requirements for biological sequence comparison

Motivation: Comparison of nucleic acid and protein sequences is a fundamental tool of modern bioinformatics. A dominant method of such string matching is the ‘seed-and-extend’ approach, in which occurrences of short subsequences called ‘seeds’ are used to search for potentially longer matches in a l...

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Veröffentlicht in:	Bioinformatics 2004-12, Vol.20 (18), p.3363-3369
Hauptverfasser:	Roberts, Michael, Hayes, Wayne, Hunt, Brian R., Mount, Stephen M., Yorke, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Databases, Genetic Fundamental and applied biological sciences. Psychology General aspects Information Storage and Retrieval - methods Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Numerical Analysis, Computer-Assisted Sequence Alignment - methods Sequence Analysis - methods
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