Comparative effects of eicosapentaenoic acid and docosahexaenoic acid on proliferation, cytokine production, and pleiotropic gene expression in Jurkat cells

Comparative effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) acid on Jurkat T cells were investigated. The following parameters were evaluated: concanavalin A (Con A) induced proliferation, production of interleukin-2 (IL-2), IL-4, IL-10, and interferon-γ (INF-γ), and expression...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2004-11, Vol.15 (11), p.657-665
Hauptverfasser:	Verlengia, Rozangela, Gorjão, Renata, Kanunfre, Carla Cristine, Bordin, Silvana, Martins De Lima, Thais, Martins, Edgair Fernandes, Curi, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity bioactive properties Biological and medical sciences cell culture Cell proliferation Cell Proliferation - drug effects Concanavalin A - pharmacology Cytokines Cytokines - biosynthesis dietary fat Docosahexaenoic acid Docosahexaenoic Acids - pharmacology Eicosapentaenoic acid Eicosapentaenoic Acid - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology gene expression Gene Expression - drug effects Humans immune response Immunobiology Interferon-gamma - biosynthesis interferons interleukin-10 Interleukin-10 - biosynthesis interleukin-2 Interleukin-2 - biosynthesis interleukin-4 Interleukin-4 - biosynthesis Jurkat cells Jurkat Cells - drug effects Jurkat Cells - metabolism Macroarray nutrient availability nutrition-genotype interaction omega-3 fatty acids Organs and cells involved in the immune response pleiotropic gene expression T-lymphocytes
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