Biosynthesis of antimalarial lignans from Holostylis reniformis

Radiolabelled precursor administrated experiments showed that lignans from Holostylis reniformis are derived from isoeugenol and that H. reniformis exhibits regioselective control of radical–radical coupling (isoeugenol radical). Regiospecific control over propenylphenol-derived lignan biosynthesis...

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Veröffentlicht in:	Phytochemistry (Oxford) 2009-03, Vol.70 (5), p.590-596
Hauptverfasser:	Messiano, Gisele B., da Silva, Tito, Nascimento, Isabele R., Lopes, Lucia M.X.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - metabolism Antiparasitic agents Aristolochiaceae Aristolochiaceae - metabolism aryltetralone Aryltetralone lignans biochemical pathways Biological and medical sciences Biosynthesis Chemical constitution Chromatography, High Pressure Liquid coniferyl alcohol Epoxylignans eugenol Fundamental and applied biological sciences. Psychology Holostylis reniformis Lignans Lignans - biosynthesis Magnetic Resonance Spectroscopy Medical sciences Neolignans Pharmacology. Drug treatments phenylalanine Plant physiology and development Propenylphenols Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet structure-activity relationships
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