Anticoagulant surface modification of titanium via layer-by-layer assembly of collagen and sulfated chitosan multilayers

Extracellular matrix (ECM)‐like biomimetic surface modification of cardiovascular implants is a promising method for improving hemocompatibility. In the present work, collagen (Col) and sulfated chitosan (SCS) multilayers were coated on pure titanium using a layer‐by‐layer (LBL) self‐assembly techni...

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Veröffentlicht in:	Journal of Biomedical Materials Research Part B 2009-06, Vol.89A (3), p.575-584
Hauptverfasser:	Li, Quan-Li, Huang, Nan, Chen, Jialong, Wan, Guojiang, Zhao, Ansa, Chen, Junying, Wang, Jin, Yang, Ping, Leng, Yongxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticoagulants - pharmacology Blood Platelets - drug effects Blood Platelets - ultrastructure Chitosan - chemistry collagen Collagen - chemistry hemocompatibility Humans Partial Thromboplastin Time Platelet Activation - drug effects Platelet Adhesiveness - drug effects self-assembly Sodium Hydroxide - pharmacology Spectroscopy, Fourier Transform Infrared sulfated chitosan surface modification Surface Properties - drug effects titanium Titanium - chemistry
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