Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity

Signalling mediated by Notch receptors is known to have multiple functions during vertebrate neural development, regulating processes like progenitor differentiation and cell type diversification. Various Notch ligands are expressed in the developing nervous system and their activities might contrib...

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Veröffentlicht in:	Developmental biology 2009-04, Vol.328 (1), p.54-65
Hauptverfasser:	Rocha, Susana Ferreira, Lopes, Susana Santos, Gossler, Achim, Henrique, Domingos
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Cell fate diversity Crosses, Genetic Delta ligands Embryo, Mammalian Heterozygote Homozygote Immunohistochemistry In Situ Hybridization Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - metabolism Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mice, Knockout Mice, Mutant Strains Models, Biological Neurogenesis Notch signaling Retina Retina - cytology Retina - embryology Retina - metabolism Spinal cord Spinal Cord - cytology Spinal Cord - embryology Spinal Cord - metabolism
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