Polyacrylamide gel containing egg white as new model for irradiation experiments using focused ultrasound

A polyacrylamide (PAA) gel containing egg white as a new model for irradiation experiments in high-intensity focused ultrasound HIFU is introduced. The gel is transparent except in thermally necrosed regions which are white. The model is similar to, and has the same benefits as, gels containing bovi...

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Veröffentlicht in:Ultrasound in medicine & biology 2004-10, Vol.30 (10), p.1419-1422
Hauptverfasser: Takegami, Kenji, Kaneko, Yukio, Watanabe, Toshiaki, Maruyama, Toshiyuki, Matsumoto, Yoichiro, Nagawa, Hirokazu
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container_end_page 1422
container_issue 10
container_start_page 1419
container_title Ultrasound in medicine & biology
container_volume 30
creator Takegami, Kenji
Kaneko, Yukio
Watanabe, Toshiaki
Maruyama, Toshiyuki
Matsumoto, Yoichiro
Nagawa, Hirokazu
description A polyacrylamide (PAA) gel containing egg white as a new model for irradiation experiments in high-intensity focused ultrasound HIFU is introduced. The gel is transparent except in thermally necrosed regions which are white. The model is similar to, and has the same benefits as, gels containing bovine serum albumin (BSA) protein, but egg is less expensive than BSA. The acoustic properties of the gel are very favorable, similar to those of soft tissues; density 1.0 g/cm 3, sound speed 1540 m/s and acoustic attenuation 0.4 dB/cm at 2 MHz. We illustrate the usefulness of the gel in visualizing HIFU lesions and introduce a new model of gastric submucosal tumor in a rabbit stomach, showing that this gel can be formed into any desired shape. Our PAA gel containing egg white is an attractive candidate for a disposable acoustic material suitable for experimental applications of HIFU. (E-mail: ktakegami-tky@umin.ac.jp)
doi_str_mv 10.1016/j.ultrasmedbio.2004.07.016
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subjects Acrylic Resins
Animals
Egg White
Gastric Mucosa - diagnostic imaging
High-intensity focused ultrasound
Models, Biological
Phantoms, Imaging
Polyacrylamide gel
Rabbits
Stomach Neoplasms - diagnostic imaging
Submucosal tumor
Tissue-mimicking phantom gel
Ultrasonic Therapy - methods
Ultrasonography
Ultrasound
title Polyacrylamide gel containing egg white as new model for irradiation experiments using focused ultrasound
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