Dpp signaling promotes the cuboidal-to-columnar shape transition of Drosophila wing disc epithelia by regulating Rho1

Morphogenesis is largely driven by changes in the shape of individual cells. However, how cell shape is regulated in developing animals is not well understood. Here, we show that the onset of TGFβ/Dpp signaling activity correlates with the transition from cuboidal to columnar cell shape in developin...

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Veröffentlicht in:Journal of cell science 2009-05, Vol.122 (9), p.1362-1373
Hauptverfasser: Widmann, Thomas J, Dahmann, Christian
Format: Artikel
Sprache:eng
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