Lymphadenopathy After BCG Vaccination in a Child with Chronic Granulomatous Disease
: We report a 15‐month‐old boy who developed an ulcer in the left axillary fold following bacillus Calmette‐Guérin vaccination. Subsequent immunologic and genetic studies led to the diagnosis of chronic granulomatous disease. His mother had “lupus‐like” lesions, described in some carriers of this d...
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| Veröffentlicht in: | Pediatric dermatology 2004-11, Vol.21 (6), p.646-651 |
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| container_title | Pediatric dermatology |
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| creator | Vieira, Ana Paula Vasconcelos, Júlia Fernandes, José Carlos Antunes, Henedina Basto, A. Sousa Macedo, Cristiana Zaman, Afsana Santos, Eugénia Melo, J. Castro Roos, Dirk |
| description | : We report a 15‐month‐old boy who developed an ulcer in the left axillary fold following bacillus Calmette‐Guérin vaccination. Subsequent immunologic and genetic studies led to the diagnosis of chronic granulomatous disease. His mother had “lupus‐like” lesions, described in some carriers of this disease, that were thus related to her son's diagnosis. Although in healthy subjects this vaccination is usually harmless, in instances of impaired immunity it may cause adverse reactions. When a vaccine‐related complication occurs, an underlying immunodeficiency should be sought. |
| doi_str_mv | 10.1111/j.0736-8046.2004.21606.x |
| format | Article |
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Sousa</creatorcontrib><creatorcontrib>Macedo, Cristiana</creatorcontrib><creatorcontrib>Zaman, Afsana</creatorcontrib><creatorcontrib>Santos, Eugénia</creatorcontrib><creatorcontrib>Melo, J. Castro</creatorcontrib><creatorcontrib>Roos, Dirk</creatorcontrib><title>Lymphadenopathy After BCG Vaccination in a Child with Chronic Granulomatous Disease</title><title>Pediatric dermatology</title><addtitle>Pediatr Dermatol</addtitle><description>: We report a 15‐month‐old boy who developed an ulcer in the left axillary fold following bacillus Calmette‐Guérin vaccination. Subsequent immunologic and genetic studies led to the diagnosis of chronic granulomatous disease. His mother had “lupus‐like” lesions, described in some carriers of this disease, that were thus related to her son's diagnosis. Although in healthy subjects this vaccination is usually harmless, in instances of impaired immunity it may cause adverse reactions. When a vaccine‐related complication occurs, an underlying immunodeficiency should be sought.</description><subject>BCG Vaccine - adverse effects</subject><subject>BCG Vaccine - immunology</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Granulocytes - immunology</subject><subject>Granulocytes - metabolism</subject><subject>Granulomatous Disease, Chronic - complications</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Lymphatic Diseases - etiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Monocytes - immunology</subject><subject>Monocytes - metabolism</subject><subject>Other diseases. Hematologic involvement in other diseases</subject><subject>Prognosis</subject><subject>Skin Ulcer - etiology</subject><issn>0736-8046</issn><issn>1525-1470</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1LAzEQhoMotlb_guSit10zu5tsehFqW6tQUPDjGqbZLE3Zj7rZ0vbfm35gr84lA3lm5uUhhAILwdfDImRpLALJEhFGjCVhBIKJcHNGusAjHkCSsnPS_YM65Mq5BWNMCgGXpAOcp1wmsks-pttyOcfMVPUS2_mWDvLWNPRpOKHfqLWtsLV1RW1FkQ7ntsjo2rZz3zZ1ZTWdNFitirrEtl45OrLOoDPX5CLHwpmb49sjX8_jz-FLMH2bvA4H00AniRQBN1pChBHPDIskl1rMcgb9PnKB4KNnkKY55FyzVM9YLIQGMUMOGGv_1c_iHrk_7F029c_KuFaV1mlTFFgZH0eJFDhISDwoD6Buaucak6tlY0tstgqY2glVC7VzpXau1E6o2gtVGz96e7yxmpUmOw0eDXrg7gig01jkXoi27sSJmEvZTz33eODWtjDbfwdQ76Pxvo1_AahYkGw</recordid><startdate>200411</startdate><enddate>200411</enddate><creator>Vieira, Ana Paula</creator><creator>Vasconcelos, Júlia</creator><creator>Fernandes, José Carlos</creator><creator>Antunes, Henedina</creator><creator>Basto, A. 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Hematologic involvement in other diseases</topic><topic>Prognosis</topic><topic>Skin Ulcer - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vieira, Ana Paula</creatorcontrib><creatorcontrib>Vasconcelos, Júlia</creatorcontrib><creatorcontrib>Fernandes, José Carlos</creatorcontrib><creatorcontrib>Antunes, Henedina</creatorcontrib><creatorcontrib>Basto, A. Sousa</creatorcontrib><creatorcontrib>Macedo, Cristiana</creatorcontrib><creatorcontrib>Zaman, Afsana</creatorcontrib><creatorcontrib>Santos, Eugénia</creatorcontrib><creatorcontrib>Melo, J. 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| ispartof | Pediatric dermatology, 2004-11, Vol.21 (6), p.646-651 |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | BCG Vaccine - adverse effects BCG Vaccine - immunology Biological and medical sciences Dermatology Granulocytes - immunology Granulocytes - metabolism Granulomatous Disease, Chronic - complications Hematologic and hematopoietic diseases Humans Infant Lymphatic Diseases - etiology Male Medical sciences Monocytes - immunology Monocytes - metabolism Other diseases. Hematologic involvement in other diseases Prognosis Skin Ulcer - etiology |
| title | Lymphadenopathy After BCG Vaccination in a Child with Chronic Granulomatous Disease |
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