Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic β-Cells

We previously described the presence of nicotinamide adenine dinucleotide phosphate reduced form [NAD(P)H]oxidase components in pancreatic β-cells and its activation by glucose, palmitic acid, and proinflammatory cytokines. In the present study, the importance of the NAD(P)H oxidase complex for panc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrinology (Philadelphia) 2009-05, Vol.150 (5), p.2197-2201
Hauptverfasser:	Morgan, D, Rebelato, E, Abdulkader, F, Graciano, M. F. R, Oliveira-Emilio, H. R, Hirata, A. E, Rocha, M. S, Bordin, S, Curi, R, Carpinelli, A. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Animals Antisense oligonucleotides Beta cells Biological and medical sciences Calcium Calcium (intracellular) Calcium Signaling - drug effects Cell activation Cells, Cultured Dose-Response Relationship, Drug Enzymatic activity Enzyme activity Enzyme Inhibitors - pharmacology Enzymes Female Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - drug effects Glucokinase Glucose Glucose - metabolism Glucose - pharmacology Glucose transporter Hydrogen Peroxide - metabolism Insulin Insulin - metabolism Insulin Secretion Insulin-Secreting Cells - drug effects Insulin-Secreting Cells - metabolism Intracellular NAD(P)H oxidase NADPH Oxidases - antagonists & inhibitors NADPH Oxidases - genetics NADPH Oxidases - physiology NADPH-diaphorase Nicotinamide Nicotinamide adenine dinucleotide Onium Compounds - pharmacology Oxidase Oxidation Oxidation-Reduction - drug effects Palmitic acid Pancreas Rats Rats, Wistar Reactive oxygen species Reactive Oxygen Species - metabolism RNA, Small Interfering - pharmacology Vertebrates: endocrinology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!