Brain Serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: Effects of major depressive episodes and severity of dysfunctional attitudes

Although brain serotonin transporter (5-HTT) density has been investigated in subjects with a history of major depressive episodes (MDE), there has never been an investigation of brain 5-HTT during a current MDE. Brain 5-HTT binding potential (BP) may have an important role during MDE due to major d...

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Veröffentlicht in:	Archives of general psychiatry 2004-12, Vol.61 (12), p.1271-1279
Hauptverfasser:	MEYER, Jeffrey H, HOULE, Sylvain, SAGRATI, Sandra, CARELLA, Anna, HUSSEY, Doug F, GINOVART, Nathalie, GOULDING, Verdell, KENNEDY, James, WILSON, Alan A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Benzylamines Biological and medical sciences Brain - diagnostic imaging Brain - metabolism Carbon Radioisotopes Depression Depressive Disorder, Major - diagnosis Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - metabolism Humans Medical sciences Membrane Glycoproteins - metabolism Membrane Transport Proteins - metabolism Mood disorders Negativism Nerve Tissue Proteins - metabolism Positron-Emission Tomography - statistics & numerical data Psychiatric Status Rating Scales - statistics & numerical data Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Serotonin - metabolism Serotonin Plasma Membrane Transport Proteins
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