Short bacterial DNA fragments: Detection in dialysate and induction of cytokines

A number of bacterial cytokine-inducing substances (CIS) such as lipopolysaccharides (LPS) and exotoxins have been detected in dialysate and may contribute to inflammation in hemodialysis patients. Short DNA fragments, oligodeoxynucleotides (ODN) of 6 to 20 nucleotides, are able to bind to Toll-like...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2004-12, Vol.15 (12), p.3207-3214
Hauptverfasser:	SCHINDLER, Ralf, BECK, Werner, DEPPISCH, Reinhold, AUSSIEKER, Mario, WILDE, Adelheid, GÖHL, Hermann, FREI, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cytokines - immunology Dialysis Solutions DNA, Bacterial - immunology DNA, Bacterial - isolation & purification Emergency and intensive care: renal failure. Dialysis management Equipment Contamination Humans In Vitro Techniques Intensive care medicine Kidney Failure, Chronic - immunology Kidney Failure, Chronic - therapy Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - microbiology Medical sciences Membranes, Artificial Nephrology. Urinary tract diseases Oligodeoxyribonucleotides - isolation & purification Pseudomonas aeruginosa - genetics Renal Dialysis Ultrafiltration
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