Blood-based transcriptomics: leukemias and beyond

In 1999, Golub et al. proposed for the first time microarray-based transcriptional profiling to be used as a new technology for the differential diagnosis of acute myeloid leukemias and acute lymphocytic leukemias. This very preliminary study sparked great enthusiasm beyond the leukemias. Over the l...

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Veröffentlicht in:	Expert review of molecular diagnostics 2009-04, Vol.9 (3), p.271-280
Hauptverfasser:	Staratschek-Jox, Andrea, Classen, Sabine, Gaarz, Andrea, Debey-Pascher, Svenja, Schultze, Joachim L
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune Diseases - diagnosis Autoimmune Diseases - genetics Blood DNA Gene expression Gene Expression Profiling - methods Genetic aspects Humans inflammation Leukemia Leukemia - classification Leukemia - diagnosis Leukemia - genetics microarray molecular diagnostics molecular profiling Oligonucleotide Array Sequence Analysis - methods Physiological aspects Risk factors RNA transcriptomics
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