Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE

Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathway and total se...

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Veröffentlicht in:	Allergy 2009-05, Vol.64 (5), p.746-753
Hauptverfasser:	Tewfik, M.A, Bossé, Y, Lemire, M, Hudson, T.J, Vallée-Smejda, S, Al-Shemari, H, Laprise, C, Desrosiers, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergies asthma Biological and medical sciences Chronic Disease Chronic obstructive pulmonary disease, asthma chronic rhinosinusitis Cross-Sectional Studies Cytokines Dermatology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Frequency - genetics Gene Frequency - immunology genetics innate immunity Genotype Genotype & phenotype Humans Hypersensitivity - genetics Hypersensitivity - immunology Immune system immunoglobulin E Immunoglobulin E - blood Immunoglobulins Interleukin-1 Receptor-Associated Kinases - genetics Interleukin-1 Receptor-Associated Kinases - immunology Linkage Disequilibrium Male Medical sciences Middle Aged Pneumology Polymorphism Polymorphism, Single Nucleotide Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Surveys and Questionnaires
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