l -Arginine Supplementation Protects Against Hepatic Ischemia–Reperfusion Lesions in Rabbits

Abstract We evaluated the effects of a substrate in the biosynthesis of nitric oxide (NO)- l -arginine (LARG)-on hepatic lesions caused by ischemia/reperfusion (I/R) injury in rabbit livers. Rabbits were pretreated with LARG (150 mg/kg IV) or saline solution 0.9% (SS) before the hepatic I/R procedur...

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Veröffentlicht in:	Transplantation proceedings 2009-04, Vol.41 (3), p.816-819
Hauptverfasser:	Taha, M.O, Simões, M.J, Haddad, M.A, Capelato, R.C, Budny, N, Matsumoto, A.H, Soares, P.C.M, Santos, W.M, Armeato, G.D, Araki, C.M, Gomes, J.S.M, Magalhães, K.G, Tersariol, I.L.S, Monteiro, H.P, Oliveira, I, Jurkiewicz, A, Caricati-Neto, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Alanine Transaminase - drug effects Animals Arginine - therapeutic use Aspartate Aminotransferases - blood Aspartate Aminotransferases - drug effects Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Gastroenterology. Liver. Pancreas. Abdomen L-Lactate Dehydrogenase - blood L-Lactate Dehydrogenase - drug effects Liver Circulation - drug effects Liver Diseases - prevention & control Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Nitric Oxide - metabolism Other diseases. Semiology Rabbits Reperfusion Injury - enzymology Reperfusion Injury - pathology Reperfusion Injury - prevention & control Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Vasoconstriction - drug effects
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