Thalidomide-derived immunomodulatory drugs as therapeutic agents

Thalidomide, a drug originally used to treat morning sickness, was removed from the market place in the early 1960s after it was found to cause serious congenital birth defects. However, thalidomide has recently been investigated in a new light following its activity in a number of chronic diseases....

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Bibliographische Detailangaben
Veröffentlicht in:	Expert opinion on biological therapy 2004-12, Vol.4 (12), p.1963-1970
Hauptverfasser:	Galustian, Christine, Labarthe, Marie-Christine, Bartlett, J Blake, Dalgleish, Angus G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - immunology Anti-Inflammatory Agents - therapeutic use Antineoplastic Agents - chemistry Antineoplastic Agents - immunology Antineoplastic Agents - therapeutic use Clinical Trials as Topic - statistics & numerical data Humans IMiDs Immunologic Factors - chemistry Immunologic Factors - immunology Immunologic Factors - therapeutic use multiple myeloma T cell costimulation Thalidomide - chemistry Thalidomide - immunology Thalidomide - therapeutic use thalidomide analogues therapeutics
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