Personality Traits, Depression, and Objectively Measured Adherence to Once-daily Prostaglandin Analog Medication in Glaucoma

PURPOSETo investigate the influence of personality traits, depression, and training on objectively measured adherence to once-daily prostaglandin analog medication. METHODSAdherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-...

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Veröffentlicht in:Journal of glaucoma 2009-04, Vol.18 (4), p.288-292
Hauptverfasser: Holló, Gábor, Kóthy, Péter, Géczy, Anna, Vargha, Péter
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container_title Journal of glaucoma
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creator Holló, Gábor
Kóthy, Péter
Géczy, Anna
Vargha, Péter
description PURPOSETo investigate the influence of personality traits, depression, and training on objectively measured adherence to once-daily prostaglandin analog medication. METHODSAdherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-administered travoprost. Before the 3-month data-collection period all patients received training on use of the device. Psychologic characteristics were measured using the State-Trait Anxiety Inventory, Eysenck Personality Questionnaire, and Beck Hopeless Scale and Depression Inventory. An adherent day was defined as travoprost instillation at 9 PM ±2 hours. RESULTSAdherence was 77% for the total period. Social desirability was higher than normal (U test, P
doi_str_mv 10.1097/IJG.0b013e31818456b9
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METHODSAdherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-administered travoprost. Before the 3-month data-collection period all patients received training on use of the device. Psychologic characteristics were measured using the State-Trait Anxiety Inventory, Eysenck Personality Questionnaire, and Beck Hopeless Scale and Depression Inventory. An adherent day was defined as travoprost instillation at 9 PM ±2 hours. RESULTSAdherence was 77% for the total period. Social desirability was higher than normal (U test, P&lt;0.0001). Seven patients (12.1%) showed mild-to-moderate depression, which was not significantly associated with decreased adherence (Kruskal-Wallis test, P=0.071). Severity of glaucoma, number of ocular and systemic medications, satisfaction with the recording device, and socio-economic characteristics had no influence on adherence. CONCLUSIONSObjectively measured adherence to once-daily prostaglandin analog medication was good, and not influenced by treatment characteristics or patient factors including mild-to-moderate depression. The elevated social desirability suggests that self-reported adherence is not a reliable measure of adherence in glaucoma.</description><identifier>ISSN: 1057-0829</identifier><identifier>EISSN: 1536-481X</identifier><identifier>DOI: 10.1097/IJG.0b013e31818456b9</identifier><identifier>PMID: 19365193</identifier><language>eng</language><publisher>United States: Lippincott Williams &amp; Wilkins, Inc</publisher><subject>Aged ; Antihypertensive Agents - administration &amp; dosage ; Anxiety Disorders - psychology ; Cloprostenol - administration &amp; dosage ; Cloprostenol - analogs &amp; derivatives ; Depressive Disorder - psychology ; Drug Monitoring - instrumentation ; Female ; Glaucoma - drug therapy ; Humans ; Intraocular Pressure - physiology ; Male ; Medication Adherence - psychology ; Ocular Hypertension - drug therapy ; Patient Education as Topic ; Personality Disorders - psychology ; Surveys and Questionnaires ; Travoprost</subject><ispartof>Journal of glaucoma, 2009-04, Vol.18 (4), p.288-292</ispartof><rights>2009 Lippincott Williams &amp; Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3505-f03f2017be4e006a08fc6346d3842e9b0fccf7d99733976c57d0d1a70bab41db3</citedby><cites>FETCH-LOGICAL-c3505-f03f2017be4e006a08fc6346d3842e9b0fccf7d99733976c57d0d1a70bab41db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19365193$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Holló, Gábor</creatorcontrib><creatorcontrib>Kóthy, Péter</creatorcontrib><creatorcontrib>Géczy, Anna</creatorcontrib><creatorcontrib>Vargha, Péter</creatorcontrib><title>Personality Traits, Depression, and Objectively Measured Adherence to Once-daily Prostaglandin Analog Medication in Glaucoma</title><title>Journal of glaucoma</title><addtitle>J Glaucoma</addtitle><description>PURPOSETo investigate the influence of personality traits, depression, and training on objectively measured adherence to once-daily prostaglandin analog medication. METHODSAdherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-administered travoprost. Before the 3-month data-collection period all patients received training on use of the device. Psychologic characteristics were measured using the State-Trait Anxiety Inventory, Eysenck Personality Questionnaire, and Beck Hopeless Scale and Depression Inventory. An adherent day was defined as travoprost instillation at 9 PM ±2 hours. RESULTSAdherence was 77% for the total period. Social desirability was higher than normal (U test, P&lt;0.0001). Seven patients (12.1%) showed mild-to-moderate depression, which was not significantly associated with decreased adherence (Kruskal-Wallis test, P=0.071). Severity of glaucoma, number of ocular and systemic medications, satisfaction with the recording device, and socio-economic characteristics had no influence on adherence. CONCLUSIONSObjectively measured adherence to once-daily prostaglandin analog medication was good, and not influenced by treatment characteristics or patient factors including mild-to-moderate depression. The elevated social desirability suggests that self-reported adherence is not a reliable measure of adherence in glaucoma.</description><subject>Aged</subject><subject>Antihypertensive Agents - administration &amp; dosage</subject><subject>Anxiety Disorders - psychology</subject><subject>Cloprostenol - administration &amp; dosage</subject><subject>Cloprostenol - analogs &amp; derivatives</subject><subject>Depressive Disorder - psychology</subject><subject>Drug Monitoring - instrumentation</subject><subject>Female</subject><subject>Glaucoma - drug therapy</subject><subject>Humans</subject><subject>Intraocular Pressure - physiology</subject><subject>Male</subject><subject>Medication Adherence - psychology</subject><subject>Ocular Hypertension - drug therapy</subject><subject>Patient Education as Topic</subject><subject>Personality Disorders - psychology</subject><subject>Surveys and Questionnaires</subject><subject>Travoprost</subject><issn>1057-0829</issn><issn>1536-481X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEFv1DAQhS0EoqXwDxDyiVNTxnESx8dVgaWoaHsoErfIsSddF2-82A7VSvx4BnWlShzsGVvvfZp5jL0VcCFAqw9XX9cXMIKQKEUv-qbtRv2MnYpWdlXTix_PqYdWVdDX-oS9yvkeoIa6Fi_ZidCya-k6ZX9uMOU4m-DLgd8m40s-5x9xnzBnH-dzbmbHN-M92uJ_Yzjwb2jyktDxldtiwtkiL5FvqFbOeBLcpJiLuQtk9DNfETrekct5awoROX2ug1ls3JnX7MVkQsY3x3rGvn_-dHv5pbrerK8uV9eVlS201QRyqkGoERsE6Az0k-1k0znZNzXqESZrJ-W0VlJq1dlWOXDCKBjN2Ag3yjP2_pG7T_HXgrkMO58tBpoR45KHTokGFLQkbB6FlpbICadhn_zOpMMgYPiX-kCpD_-nTrZ3R_4y7tA9mY4xP3EfYigU-M-wPGAatmhC2Q5ASwmh-6oG0NDQs6JD4_wFw4KPiw</recordid><startdate>200904</startdate><enddate>200904</enddate><creator>Holló, Gábor</creator><creator>Kóthy, Péter</creator><creator>Géczy, Anna</creator><creator>Vargha, Péter</creator><general>Lippincott Williams &amp; Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200904</creationdate><title>Personality Traits, Depression, and Objectively Measured Adherence to Once-daily Prostaglandin Analog Medication in Glaucoma</title><author>Holló, Gábor ; Kóthy, Péter ; Géczy, Anna ; Vargha, Péter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3505-f03f2017be4e006a08fc6346d3842e9b0fccf7d99733976c57d0d1a70bab41db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aged</topic><topic>Antihypertensive Agents - administration &amp; dosage</topic><topic>Anxiety Disorders - psychology</topic><topic>Cloprostenol - administration &amp; dosage</topic><topic>Cloprostenol - analogs &amp; derivatives</topic><topic>Depressive Disorder - psychology</topic><topic>Drug Monitoring - instrumentation</topic><topic>Female</topic><topic>Glaucoma - drug therapy</topic><topic>Humans</topic><topic>Intraocular Pressure - physiology</topic><topic>Male</topic><topic>Medication Adherence - psychology</topic><topic>Ocular Hypertension - drug therapy</topic><topic>Patient Education as Topic</topic><topic>Personality Disorders - psychology</topic><topic>Surveys and Questionnaires</topic><topic>Travoprost</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holló, Gábor</creatorcontrib><creatorcontrib>Kóthy, Péter</creatorcontrib><creatorcontrib>Géczy, Anna</creatorcontrib><creatorcontrib>Vargha, Péter</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of glaucoma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holló, Gábor</au><au>Kóthy, Péter</au><au>Géczy, Anna</au><au>Vargha, Péter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Personality Traits, Depression, and Objectively Measured Adherence to Once-daily Prostaglandin Analog Medication in Glaucoma</atitle><jtitle>Journal of glaucoma</jtitle><addtitle>J Glaucoma</addtitle><date>2009-04</date><risdate>2009</risdate><volume>18</volume><issue>4</issue><spage>288</spage><epage>292</epage><pages>288-292</pages><issn>1057-0829</issn><eissn>1536-481X</eissn><abstract>PURPOSETo investigate the influence of personality traits, depression, and training on objectively measured adherence to once-daily prostaglandin analog medication. METHODSAdherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-administered travoprost. Before the 3-month data-collection period all patients received training on use of the device. Psychologic characteristics were measured using the State-Trait Anxiety Inventory, Eysenck Personality Questionnaire, and Beck Hopeless Scale and Depression Inventory. An adherent day was defined as travoprost instillation at 9 PM ±2 hours. RESULTSAdherence was 77% for the total period. Social desirability was higher than normal (U test, P&lt;0.0001). Seven patients (12.1%) showed mild-to-moderate depression, which was not significantly associated with decreased adherence (Kruskal-Wallis test, P=0.071). Severity of glaucoma, number of ocular and systemic medications, satisfaction with the recording device, and socio-economic characteristics had no influence on adherence. CONCLUSIONSObjectively measured adherence to once-daily prostaglandin analog medication was good, and not influenced by treatment characteristics or patient factors including mild-to-moderate depression. The elevated social desirability suggests that self-reported adherence is not a reliable measure of adherence in glaucoma.</abstract><cop>United States</cop><pub>Lippincott Williams &amp; Wilkins, Inc</pub><pmid>19365193</pmid><doi>10.1097/IJG.0b013e31818456b9</doi><tpages>5</tpages></addata></record>
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subjects Aged
Antihypertensive Agents - administration & dosage
Anxiety Disorders - psychology
Cloprostenol - administration & dosage
Cloprostenol - analogs & derivatives
Depressive Disorder - psychology
Drug Monitoring - instrumentation
Female
Glaucoma - drug therapy
Humans
Intraocular Pressure - physiology
Male
Medication Adherence - psychology
Ocular Hypertension - drug therapy
Patient Education as Topic
Personality Disorders - psychology
Surveys and Questionnaires
Travoprost
title Personality Traits, Depression, and Objectively Measured Adherence to Once-daily Prostaglandin Analog Medication in Glaucoma
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