Expression of tissue-type transglutaminase (tTG) and the effect of tTG inhibitor on the hippocampal CA1 region after transient ischemia in gerbils

Abstract Chronological changes of tissue-type transglutaminase (tTG) were observed in the hippocampal CA1 region after transient forebrain ischemia in gerbils. In the sham-operated group, tTG immunoreactivity was weakly detected in blood vessels which were immunostained with platelet endothelial cel...

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Veröffentlicht in:	Brain research 2009-03, Vol.1263, p.134-142
Hauptverfasser:	Hwang, In Koo, Yoo, Ki-Yeon, Yi, Sun Shin, Kim, Il Yong, Hwang, Hye Sook, Lee, Kyung-Yul, Choi, Sun Mi, Lee, In Se, Yoon, Yeo Sung, Kim, Soo Youl, Won, Moo Ho, Seong, Je Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Benzoxazines Biological and medical sciences Blood vessel Blood Vessels - enzymology Blotting, Western Brain Ischemia - drug therapy Brain Ischemia - enzymology Cystamine Cystamine - therapeutic use Enzyme Inhibitors - therapeutic use Fluorescent Antibody Technique Gerbillinae GTP-Binding Proteins - antagonists & inhibitors GTP-Binding Proteins - metabolism Hippocampus - blood supply Hippocampus - drug effects Hippocampus - enzymology Iba-1 Immunohistochemistry Ischemia Male Medical sciences Microglia Microglia - metabolism Motor Activity - drug effects Neurology Neurons - drug effects Neurons - physiology Neuroprotective Agents - therapeutic use Oxazines PECAM-1 Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Reperfusion Injury - drug therapy Reperfusion Injury - physiopathology Transglutaminase 2 Transglutaminases - antagonists & inhibitors Transglutaminases - metabolism Vascular diseases and vascular malformations of the nervous system
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