Cancer/testis antigen CT45: Analysis of mRNA and protein expression in human cancer

CT45 is a cancer/testis gene that we previously identified by massively parallel signature sequencing. Encoded by a multigene family on chromosome X, CT45 showed restricted mRNA expression to normal testis and various cancers. In this study, monoclonal antibodies were generated against recombinant C...

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Veröffentlicht in:	International journal of cancer 2009-06, Vol.124 (12), p.2893-2898
Hauptverfasser:	Chen, Yao‐Tseng, Hsu, Melinda, Lee, Peishan, Shin, Sandra J., Mhawech‐Fauceglia, Paulette, Odunsi, Kunle, Altorki, Nasser K., Song, Chao‐Jun, Jin, Bo‐Quan, Simpson, Andrew J., Old, Lloyd J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - secondary Animals Antibodies, Monoclonal - immunology Antibodies, Monoclonal - metabolism Antigens, Neoplasm - genetics Antigens, Neoplasm - immunology Antigens, Neoplasm - metabolism Biological and medical sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology cancer vaccine cancer/testis antigen Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - secondary Female Humans Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Medical sciences Mice Mice, Inbred BALB C Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Prognosis Recombinant Proteins - genetics Recombinant Proteins - immunology Recombinant Proteins - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Testicular Neoplasms - genetics Testicular Neoplasms - metabolism Testicular Neoplasms - pathology Tissue Array Analysis tumor antigen Tumors
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