Early brain temperature elevation and anaerobic metabolism in human acute ischaemic stroke

Early after acute ischaemic stroke, elevation of brain temperature might augment tissue metabolic rate and conversion of ischaemic but viable tissue to infarction. This might explain the observed link between pyrexia, severe stroke and poor outcome. We tested this hypothesis by measuring brain tempe...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2009-04, Vol.132 (4), p.955-964
Hauptverfasser:	Karaszewski, Bartosz, Wardlaw, Joanna M., Marshall, Ian, Cvoro, Vera, Wartolowska, Karolina, Haga, Kristin, Armitage, Paul A., Bastin, Mark E., Dennis, Martin S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Body Temperature - physiology Brain - metabolism Brain - physiopathology Brain Ischemia - metabolism Brain Ischemia - physiopathology brain temperature Fever - etiology Fever - metabolism Fever - physiopathology Humans ischaemic stroke lactate metabolism Lactic Acid - metabolism Magnetic Resonance Imaging - methods Magnetic Resonance Spectroscopy - methods Medical sciences Middle Aged MR spectroscopy Neurology Prospective Studies pyrexia Stroke - complications Stroke - metabolism Stroke - physiopathology Time Factors Vascular diseases and vascular malformations of the nervous system
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